(a)
To determine: The amino acid sequence of the opioid leucine enkephalin and explain the consistency of the structure with the given information about its complete hydrolysis, amino acid analysis, treatment with FDNB, chromatography, and complete digestion of the peptide with chymotrypsin.
Introduction:
In the given scenario, a group of peptides are isolated from normal brain tissue. These peptides influence nerve transmission in some parts of the brain. The isolated proteins are also known as opioids as they bind to some specific receptors to which opiate (naloxone and morphine) drugs bind.
(b)
To determine: The amino acid sequence of the opioid leucine enkephaline and explain the consistency of the structure with the information about its complete hydrolysis, amino acid analysis, treatment with FDNB, chromatography, and complete digestion of the peptide with chymotrypsin.
Introduction:
In the given scenario, a group of peptides are isolated from normal brain tissue. These peptides influence nerve transmission in some parts of the brain. The isolated proteins are also known as opioids as they bind to some specific receptors to which opiate (naloxone and morphine) drugs bind.
(c)
To determine: The amino acid sequence of the opioid leucine enkephaline and explain the consistency of the structure with the information about its complete hydrolysis, amino acid analysis, treatment with FDNB, chromatography, and complete digestion of the peptide with chymotrypsin.
Introduction:
In the given scenario, a group of peptides are isolated from normal brain tissue. These peptides influence nerve transmission in some parts of the brain. The isolated proteins are also known as opioids as they bind to some specific receptors to which opiate (naloxone and morphine) drugs bind.
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Chapter 3 Solutions
SaplingPlus for Lehninger Principles of Biochemistry (Six-Month Access)
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