MICROBIOLOGY W/ACCESS
MICROBIOLOGY W/ACCESS
4th Edition
ISBN: 9781266808685
Author: Cowan
Publisher: MCG
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Chapter 3, Problem 13TF
Summary Introduction

Introduction:

The microscope becomes effective with three properties. These properties are: contrast, resolution, and magnification. Magnification is the increase in the size of an object under microscope to make it clearly visible. Magnification is the result of refraction of light beam or electron beam when it passes through a lens.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
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