BIOL:CONCEPT+INVEST.ETEXT
BIOL:CONCEPT+INVEST.ETEXT
5th Edition
ISBN: 9781264154173
Author: Hoefnagels
Publisher: MCG
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Chapter 29.7, Problem 2MC
Summary Introduction

To describe:

The data given in figure 29.21 and the conclusions that researchers drew from these data.

Concept introduction:

Mutations are the changes that take place in the genes of any organism. Genes are those portions of chromosomes that code a functional protein. All the proteins, traits, features and factors that are present in an organism are a result of genes present in an organism. Mutations in these genes make them non-functional or cause the genes to make a defective protein that finally and mostly are harmful and deleterious for that organism in which mutation take place.

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Explain: Healthy Cell Function Overview→ Briefly describe how a healthy cell usually works: metabolism (ATP production), pH balance, glycogen storage, ion transport, enzymes, etc. Gene Mutation and Genetics Part→ Focus on the autosomal recessive mutation and explain: How gene mutation affects the cell. How autosomal inheritance works. Compare the normal and mutated gene sequences simply. → Talk about possible consequences of a faulty hydrolytic enzyme.
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Explain down bellow what happens to the cell: Decreased pH in mitochondria Increased ATP Decreased pH in cytosol Increased hydrolysis Decreasing glycogen and triglycerides Increased MAP kinase activity Poor ion transport → For each one:→ What normally happens?→ What is wrong now?→ How does it mess up the cell?
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