Fundamentals of General, Organic, and Biological Chemistry, Books a la Carte Edition; Modified Mastering Chemistry with Pearson eText -- ValuePack ... and Biological Chemistry (4th Edition)
4th Edition
ISBN: 9780134465715
Author: John E. McMurry, David S. Ballantine
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Question
Chapter 29, Problem 29.64GP
Interpretation Introduction
Interpretation:
The compounds which are expected to cross the BBB the easiest and the compounds which are expected to cross the BBB the hardest has to be given and also provide a chemical rationale for the answer.
Concept introduction:
Blood-brain barrier (BBB) is made up membrane lipids.
The breaching of BBB is depending upon the solubility of substances in the membrane.
Alcohols are very soluble in lipids.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Match the three types of neurotransmitters to their relative size (largest to smallest):
Largest
Peptide neurotransmitter
✓
Second largest
[Choose]
Smallest
>
[Choose ]
[Choose ]
Amino acid neurotransmitter
Peptide neurotransmitter
Amine neurotransmitter
need help not sure why its wrong please help
Why the 2nd choice is correct?
Chapter 29 Solutions
Fundamentals of General, Organic, and Biological Chemistry, Books a la Carte Edition; Modified Mastering Chemistry with Pearson eText -- ValuePack ... and Biological Chemistry (4th Edition)
Ch. 29.1 - Prob. 29.1KCPCh. 29.3 - Prob. 29.1CIAPCh. 29.3 - Prob. 29.2CIAPCh. 29.3 - Prob. 29.3CIAPCh. 29.3 - Prob. 29.4CIAPCh. 29.3 - Match each term in the (a)(e) group with its...Ch. 29.5 - Prob. 29.3KCPCh. 29.5 - Prob. 29.4PCh. 29.5 - Prob. 29.5PCh. 29.8 - Prob. 29.5CIAP
Ch. 29.8 - Prob. 29.6CIAPCh. 29.8 - One of the more advanced blood tests used to...Ch. 29 - Body fluids occupy two different compartments,...Ch. 29 - Prob. 29.7UKCCh. 29 - Prob. 29.8UKCCh. 29 - Prob. 29.9UKCCh. 29 - Prob. 29.10UKCCh. 29 - Prob. 29.11UKCCh. 29 - Prob. 29.12UKCCh. 29 - Prob. 29.13APCh. 29 - Prob. 29.14APCh. 29 - Prob. 29.15APCh. 29 - Prob. 29.16APCh. 29 - Prob. 29.17APCh. 29 - Prob. 29.18APCh. 29 - Prob. 29.19APCh. 29 - Prob. 29.20APCh. 29 - Prob. 29.21APCh. 29 - Prob. 29.22APCh. 29 - Prob. 29.23APCh. 29 - What are the three main types of cells found in...Ch. 29 - Prob. 29.25APCh. 29 - Prob. 29.26APCh. 29 - Prob. 29.27APCh. 29 - Prob. 29.28APCh. 29 - Prob. 29.29APCh. 29 - Prob. 29.30APCh. 29 - Prob. 29.31APCh. 29 - Prob. 29.32APCh. 29 - Prob. 29.33APCh. 29 - Prob. 29.34APCh. 29 - Prob. 29.35APCh. 29 - Prob. 29.36APCh. 29 - Prob. 29.37APCh. 29 - Prob. 29.38APCh. 29 - Prob. 29.39APCh. 29 - Prob. 29.40APCh. 29 - Prob. 29.41APCh. 29 - Prob. 29.42APCh. 29 - What color is deoxyhemoglobin? Why?Ch. 29 - Prob. 29.44APCh. 29 - Prob. 29.45APCh. 29 - Prob. 29.46APCh. 29 - Prob. 29.47APCh. 29 - Prob. 29.48APCh. 29 - Prob. 29.49APCh. 29 - Prob. 29.50APCh. 29 - Prob. 29.51APCh. 29 - Prob. 29.52APCh. 29 - Prob. 29.53APCh. 29 - Prob. 29.54APCh. 29 - Prob. 29.55CPCh. 29 - Prob. 29.56CPCh. 29 - Prob. 29.57CPCh. 29 - How does active transport differ from osmosis?Ch. 29 - Prob. 29.59CPCh. 29 - Prob. 29.60CPCh. 29 - Prob. 29.61CPCh. 29 - Prob. 29.62CPCh. 29 - Have each member of your group choose an energy...Ch. 29 - Prob. 29.64GPCh. 29 - Prob. 29.65GP
Knowledge Booster
Similar questions
- a) What are the differences between the Direct & Indirect Immunofluorescence Assays? (0.5 mark) b) What are the advantages of the Indirect Immunofluorescence Assays? (0.5 mark) c) A Super-Resolution Imaging Technique was developed in 2018 using imidazole, a His-tag ligand conjugated with a fluorophore to report the presence of a recombinant His-tag protein target, (Sci Rep, 2018, 8:5507). How does this technique improve the image quality? (2 marks)arrow_forwarda) What are the differences between the Direct & Indirect Immunofluorescence Assays? b) What are the advantages of the Indirect Immunofluorescence Assays? c) A Super-Resolution Imaging Technique was developed in 2018 using imidazole, a His-tag ligand conjugated with a fluorophore to report the presence of a recombinant His-tag protein target, (Sci Rep, 2018, 8:5507). How does this technique improve the image quality?arrow_forwardCalculate the number of ATP produced from oxidation of 1 molecule of glucosearrow_forward
- Example 1: 1. Suppose an enzyme (MW = 5,000 g/mole) has a concentration of 0.05 mg/L. If the kcat is 1 x 10 s, what is the theoretical maximum reaction velocity for the enzyme? A) 1050 µM/s. B) 100 µM/s. C) 150 μM/s. D) 105 μM/s.arrow_forwardIn 1956, E. P. Kennedy and S. B. Weiss published their study of membrane lipid phosphatidylcholine (lecithin) synthesis in rat liver. Their hypothesis was that phosphocholine joined with some cellular component to yield lecithin. In an earlier experiment, incubating 32 P-labeled phosphocholine at physiological temperature (37 °C) with broken cells from rat liver yielded labeled lecithin. This became their assay for the enzymes involved in lecithin synthesis. Determine the optimal pH for this enzyme and characterize the enzyme activity at different pH values. -O-P-O-CH2-CH₁₂-N(CH3)3 Phosphocholine H₂C-O-C-R HC-O-C-R2 + + + Cell fraction + ? HC-O-P-O-CH₁₂-CH₂-N(CH), O Phosphatidylcholine The researchers then centrifuged the broken cell preparation to separate the membranes from the soluble proteins. They tested three preparations: whole extract, membranes, and soluble proteins. Table 1 summarizes the results. Table 1: Cell fraction requirement for incorporation of 32p-phosphocholine into…arrow_forwardResearchers isolated an unknown substance, X, from rabbit muscle. They determined its structure from the following observations and experiments. (a) Qualitative analysis showed that X was composed entirely of C, H, and O. A weighed sample of X was completely oxidized and the H2O and CO2 produced were measured. This quantitative analysis revealed that X contained 40.00% C, 6.71% H, and 53.29% O by weight. (b) The molecular mass of X, as determined by mass spectrometry, was 90.00 atomic mass units (u). (c) Infrared spectroscopy showed that X contained one double bond. (d) X dissolved readily in water, and the solution demonstrated optical activity when tested in a polarimeter. (e) The aqueous solution of X is acidic. What is the empirical formula of X?arrow_forward
- Show work. don't give Ai generated solution....give correct solutionarrow_forwardBiochemistry What is the process of "transamination" in either the muscles or the liver, that involves keto acid or glutamic acid? Please explain how the steps work. Thank you!arrow_forwardBiochemistry Please help. Thank you What is the importance of glutamic acid in the metabolism of nitrogen from amino acids? (we know therole; it’s used to remove the nitrogen from amino acids so that the remaining carbon skeleton can bebroken down by the “usual” pathways, but what is the important, unique role that only glutamicacid/glutamate can do?)arrow_forward
- Biochemistry Please help. Thank you When carbamyl phosphate is joined to L-ornathine, where does the energy for the reaction come from?arrow_forwardBiochemistry Question Please help. Thank you What is the function of glutamate dehydrogenase?arrow_forwardBiochemistry Question Please help. Thank you How and why does a high protein diet affect the enzymes of the urea cycle?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning- Essentials of Pharmacology for Health ProfessionsNursingISBN:9781305441620Author:WOODROWPublisher:CengageSurgical Tech For Surgical Tech Pos CareHealth & NutritionISBN:9781337648868Author:AssociationPublisher:Cengage
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Essentials of Pharmacology for Health Professions
Nursing
ISBN:9781305441620
Author:WOODROW
Publisher:Cengage
Surgical Tech For Surgical Tech Pos Care
Health & Nutrition
ISBN:9781337648868
Author:Association
Publisher:Cengage