(a) Interpretation: The basis of inhibition of poly-A and RNA synthesis by cordycepin should be determined. Concept introduction: RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

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Answer 1

Question

Chapter 29, Problem 15P

Interpretation Introduction

(a)

Interpretation:

The basis of inhibition of poly-A and RNA synthesis by cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Interpretation Introduction

(b)

Interpretation:

The reason for the high sensitivity of poly-A synthesis than other RNAs to cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Interpretation Introduction

(c)

Interpretation:

Whether the cordycepin is required to modify or not to exert its effect should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

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The preferred substrate is T because the enzyme half-saturates at 7.00 mM for T, but requires 28.0 mM for U, and 112 mM for S. b Question Content Area The rate constant k 2 with substrate S is 9.60×107 sec-1, with substrate T, k 2 = 6.00×104 sec-1, and with substrate U, k 2 = 2.40×106 sec-1. Calculate the catalytic efficiency with S, T, and U. Catalytic efficiency with S = Catalytic efficiency with T = Catalytic efficiency with U = Does enzyme A use substrate S, substrate T, or substrate U with greater catalytic efficiency?

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Answer 2

Question

Chapter 29, Problem 15P

Interpretation Introduction

(a)

Interpretation:

The basis of inhibition of poly-A and RNA synthesis by cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Interpretation Introduction

(b)

Interpretation:

The reason for the high sensitivity of poly-A synthesis than other RNAs to cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Interpretation Introduction

(c)

Interpretation:

Whether the cordycepin is required to modify or not to exert its effect should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

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Answer 3

Question

Chapter 29, Problem 15P

Interpretation Introduction

(a)

Interpretation:

The basis of inhibition of poly-A and RNA synthesis by cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Interpretation Introduction

(b)

Interpretation:

The reason for the high sensitivity of poly-A synthesis than other RNAs to cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Interpretation Introduction

(c)

Interpretation:

Whether the cordycepin is required to modify or not to exert its effect should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

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Answer 4

Question

Chapter 29, Problem 15P

Interpretation Introduction

(a)

Interpretation:

The basis of inhibition of poly-A and RNA synthesis by cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Interpretation Introduction

(b)

Interpretation:

The reason for the high sensitivity of poly-A synthesis than other RNAs to cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Interpretation Introduction

(c)

Interpretation:

Whether the cordycepin is required to modify or not to exert its effect should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Expert Solution & Answer

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Answer 5

Chapter 29, Problem 15P

Interpretation Introduction

(a)

Interpretation:

The basis of inhibition of poly-A and RNA synthesis by cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Interpretation Introduction

(b)

Interpretation:

The reason for the high sensitivity of poly-A synthesis than other RNAs to cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Interpretation Introduction

(c)

Interpretation:

Whether the cordycepin is required to modify or not to exert its effect should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Answer 6

Chapter 29, Problem 15P

Interpretation Introduction

(a)

Interpretation:

The basis of inhibition of poly-A and RNA synthesis by cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Answer 7

Chapter 29, Problem 15P

Interpretation Introduction

(a)

Interpretation:

The basis of inhibition of poly-A and RNA synthesis by cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Answer 8

Interpretation Introduction

(b)

Interpretation:

The reason for the high sensitivity of poly-A synthesis than other RNAs to cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Answer 9

Interpretation Introduction

(b)

Interpretation:

The reason for the high sensitivity of poly-A synthesis than other RNAs to cordycepin should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Answer 10

Interpretation Introduction

(c)

Interpretation:

Whether the cordycepin is required to modify or not to exert its effect should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Answer 11

Interpretation Introduction

(c)

Interpretation:

Whether the cordycepin is required to modify or not to exert its effect should be determined.

Concept introduction:

RNA synthesis (transcription) is the synthesis of an RNA molecule from the nucleotide’s adenine, cytosine, guanine, or uracil. The nucleotides are combined together by the enzyme RNA Polymerase.

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 29 - Prob. 1P Ch. 29 - Prob. 2P Ch. 29 - Prob. 3P Ch. 29 - Prob. 4P Ch. 29 - Prob. 5P Ch. 29 - Prob. 6P Ch. 29 - Prob. 7P Ch. 29 - Prob. 8P Ch. 29 - Prob. 9P Ch. 29 - Prob. 10P

Solution Summary: The author explains the basis of inhibition of poly-A and RNA synthesis by cordycepin.

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