The statement that “Mushrooms are like the tips of icebergs”. Introduction: Basidiocarp is formed from the dikaryotic secondary mycelium. These are reproductive structure and contain gills. These gills have basidia cells which undergo karyogamy and meiosis to form spores. These fruiting bodies are formed by members of Basidiomycetes.

Question

1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine: (a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip MAKE SURE ANSWERS HAVE UNITS if appropriate. SHOW ALL WORK, including equation used, variables used and each step to your solution.

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Question

Chapter 29, Problem 14TYU

Summary Introduction

To explain: The statement that “Mushrooms are like the tips of icebergs”.

Introduction: Basidiocarp is formed from the dikaryotic secondary mycelium. These are reproductive structure and contain gills. These gills have basidia cells which undergo karyogamy and meiosis to form spores. These fruiting bodies are formed by members of Basidiomycetes.

Summary Introduction

To explain: Whether the absence of mushrooms in an individual’s lawn can be concluded as “no fungi live there”.

Introduction: Basidiocarp is formed from the dikaryotic secondary mycelium. These are reproductive structure and contain gills. These gills have basidia cells which undergo karyogamy and meiosis to form spores. These fruiting bodies are formed by members of Basidiomycetes.

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1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine: (a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip MAKE SURE ANSWERS HAVE UNITS if appropriate. SHOW ALL WORK, including equation used, variables used and each step to your solution.

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