BIOLOGY
4th Edition
ISBN: 9781266739606
Author: Hoefnagels
Publisher: MCG
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Chapter 28.4, Problem 5MC
Summary Introduction
To determine:
The affect of darkness and light on melatonin secretion.
Concept introduction:
Melatonin is a hormone which is naturally produced in the body by the pineal gland. The pineal gland secretes melatonin in sync with our circadian rhythms. Melatonin’s primary function in the body is to regulate the sleep wake cycle.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 28 Solutions
BIOLOGY
Ch. 28.1 - Prob. 1MCCh. 28.1 - Prob. 2MCCh. 28.1 - Prob. 3MCCh. 28.1 - Prob. 4MCCh. 28.1 - Prob. 5MCCh. 28.2 - Prob. 1MCCh. 28.2 - Describe the locations of the receptors that bind...Ch. 28.2 - Prob. 3MCCh. 28.2 - Prob. 4MCCh. 28.3 - Prob. 1MC
Ch. 28.3 - Prob. 2MCCh. 28.4 - Prob. 1MCCh. 28.4 - Prob. 2MCCh. 28.4 - Prob. 3MCCh. 28.4 - Prob. 4MCCh. 28.4 - Prob. 5MCCh. 28.5 - Prob. 1MCCh. 28.5 - Prob. 2MCCh. 28.6 - Prob. 1MCCh. 28.6 - Prob. 2MCCh. 28 - The effect of a water-soluble peptide hormone such...Ch. 28 - Prob. 2MCQCh. 28 - Prob. 3MCQCh. 28 - Prob. 4MCQCh. 28 - Prob. 5MCQCh. 28 - Prob. 6MCQCh. 28 - To increase male fertility, it would be logical to...Ch. 28 - How does the endocrine system interact with the...Ch. 28 - Prob. 2WIOCh. 28 - Prob. 3WIOCh. 28 - Sketch the mechanisms of water-soluble and...Ch. 28 - Give two examples of hormones counteracting the...Ch. 28 - Alcohol and caffeine inhibit the effects of...Ch. 28 - Prob. 7WIOCh. 28 - Prob. 8WIOCh. 28 - Prob. 9WIOCh. 28 - How might insulin-producing stem cells...Ch. 28 - Prob. 11WIOCh. 28 - Prob. 12WIOCh. 28 - Prob. 1PITCh. 28 - Connect each hormone discussed in this chapter to...Ch. 28 - Prob. 3PIT
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