BIOLOGY:ESSENTIALS NSU (LL)-W/ACCESS
BIOLOGY:ESSENTIALS NSU (LL)-W/ACCESS
3rd Edition
ISBN: 9781265143862
Author: Hoefnagels
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 28, Problem 8MCQ
Summary Introduction

Introduction:

Kidneys play a significant role in filtering the waste substances from the blood and eliminating them as urine. The basic functional unit of a kidney is a nephron. Nephrons are coiled tubes that consist of the following parts glomerulus, proximal convoluted tubule, Henle's loop, distal convoluted tubule, and collecting ducts. Each part performs a specific function in urine formation.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

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BIOLOGY:ESSENTIALS NSU (LL)-W/ACCESS

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