BSC 1005 PKG-W/MOD. MAST. ACCESS >CI<
17th Edition
ISBN: 9781269683364
Author: Reece
Publisher: Pearson Custom Publishing
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Chapter 28, Problem 7TYK
Summary Introduction
To determine: The flaws in the given experiment to test an SSRI in a large number of individuals with depression.
Introduction: Selective serotonin reuptake inhibitor (SSRI) is an antidepressant that is given to a patient with a major depressive disorder. SSRI is a regulator of serotonin that regulates mood disorders by increasing the serotonin level at the synapse.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 28 Solutions
BSC 1005 PKG-W/MOD. MAST. ACCESS >CI<
Ch. 28 - Test your understanding of the nervous system by...Ch. 28 - Fill in the blanks to match some brain structures...Ch. 28 - What causes a nerve signal to move from one end of...Ch. 28 - Prob. 4TYKCh. 28 - Prob. 5TYKCh. 28 - Anesthetics block pain by blocking the...Ch. 28 - Prob. 7TYKCh. 28 - Using microelectrodes, a researcher recorded nerve...Ch. 28 - Prob. 9TYK
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