The causative agent of AIDS is human immunodeficiency virus. To treat the infections of HIV virus, HAART (highly active antiretroviral therapy) is used. The HAART therapy is the combination of three antiviral drugs. These drugs inhibit the replication of virus.

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Chapter 27, Problem 7U

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The causative agent of AIDS is human immunodeficiency virus. To treat the infections of HIV virus, HAART (highly active antiretroviral therapy) is used. The HAART therapy is the combination of three antiviral drugs. These drugs inhibit the replication of virus.

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2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0 Note that a µCi is a measure of the amount of radioactivity and hence is a measure of the amount of drug present. Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this…

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Question

Chapter 27, Problem 7U

Summary Introduction

Introduction:

The causative agent of AIDS is human immunodeficiency virus. To treat the infections of HIV virus, HAART (highly active antiretroviral therapy) is used. The HAART therapy is the combination of three antiviral drugs. These drugs inhibit the replication of virus.

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Chapter 27, Problem 7U

Summary Introduction

Introduction:

The causative agent of AIDS is human immunodeficiency virus. To treat the infections of HIV virus, HAART (highly active antiretroviral therapy) is used. The HAART therapy is the combination of three antiviral drugs. These drugs inhibit the replication of virus.

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Question

Chapter 27, Problem 7U

Summary Introduction

Introduction:

The causative agent of AIDS is human immunodeficiency virus. To treat the infections of HIV virus, HAART (highly active antiretroviral therapy) is used. The HAART therapy is the combination of three antiviral drugs. These drugs inhibit the replication of virus.

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Answer 5

Chapter 27, Problem 7U

Summary Introduction

Introduction:

The causative agent of AIDS is human immunodeficiency virus. To treat the infections of HIV virus, HAART (highly active antiretroviral therapy) is used. The HAART therapy is the combination of three antiviral drugs. These drugs inhibit the replication of virus.

Answer 6

Chapter 27, Problem 7U

Summary Introduction

Introduction:

The causative agent of AIDS is human immunodeficiency virus. To treat the infections of HIV virus, HAART (highly active antiretroviral therapy) is used. The HAART therapy is the combination of three antiviral drugs. These drugs inhibit the replication of virus.

Answer 7

Chapter 27, Problem 7U

Summary Introduction

Introduction:

The causative agent of AIDS is human immunodeficiency virus. To treat the infections of HIV virus, HAART (highly active antiretroviral therapy) is used. The HAART therapy is the combination of three antiviral drugs. These drugs inhibit the replication of virus.

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Ch. 27 - The reverse transcriptase enzyme is active in...Ch. 27 - Which of the following is NOT part of a virus? a....Ch. 27 - Which of the following is common in animal viruses...Ch. 27 - Which of the following would NOT be part of the...Ch. 27 - A process by which a virus may change a benign...Ch. 27 - Prob. 6U Ch. 27 - Prob. 7U Ch. 27 - Prob. 1A Ch. 27 - The idea of a protein that was an infectious agent...Ch. 27 - Bacterial viruses and animal viruses are similar...

The causative agent of AIDS is human immunodeficiency virus. To treat the infections of HIV virus, HAART (highly active antiretroviral therapy) is used. The HAART therapy is the combination of three antiviral drugs. These drugs inhibit the replication of virus.

Solution Summary: The author explains that the combination of three antiviral drugs in HAART reduces the viral load from the bloodstream of infected patients.

Introduction:

The causative agent of AIDS is human immunodeficiency virus. To treat the infections of HIV virus, HAART (highly active antiretroviral therapy) is used. The HAART therapy is the combination of three antiviral drugs. These drugs inhibit the replication of virus.

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Chapter 27 Solutions

The causative agent of AIDS is human immunodeficiency virus. To treat the infections of HIV virus, HAART (highly active antiretroviral therapy) is used. The HAART therapy is the combination of three antiviral drugs. These drugs inhibit the replication of virus.

Solution Summary: The author explains that the combination of three antiviral drugs in HAART reduces the viral load from the bloodstream of infected patients.

Introduction: The causative agent of AIDS is human immunodeficiency virus. To treat the infections of HIV virus, HAART (highly active antiretroviral therapy) is used. The HAART therapy is the combination of three antiviral drugs. These drugs inhibit the replication of virus.

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Chapter 27 Solutions

Introduction:

The causative agent of AIDS is human immunodeficiency virus. To treat the infections of HIV virus, HAART (highly active antiretroviral therapy) is used. The HAART therapy is the combination of three antiviral drugs. These drugs inhibit the replication of virus.