Chapter 27, Problem 27.56P

(a)

Interpretation Introduction

Interpretation:

Whether the side chain of amino acid Leucine in plasma protein is found to be present on surface of the globular protein and in contact with aqueous environment or shielded from the aqueous environment has to be explained.

Concept Introduction:

Tendency of non-polar groups to cluster themselves and shield from the contact with an aqueous environment is known as Hydrophobic effect.  This effect plays an important role in folding of the polypeptide chain into three-dimensional shape. The nonpolar groups are excluded without interacting with molecules of water as water molecules stick through hydrogen bonding.  Hydrophilic side chains are the ones that interact with the aqueous environment by forming hydrogen bonds.

(b)

Interpretation Introduction

Interpretation:

Whether the side chain of amino acid Arginine in plasma protein is found to be present on surface of the globular protein and in contact with aqueous environment or shielded from the aqueous environment has to be explained.

Concept Introduction:

Tendency of non-polar groups to cluster themselves and shield from the contact with an aqueous environment is known as Hydrophobic effect.  This effect plays an important role in folding of the polypeptide chain into three-dimensional shape. The nonpolar groups are excluded without interacting with molecules of water as water molecules stick through hydrogen bonding.  Hydrophilic side chains are the ones that interact with the aqueous environment by forming hydrogen bonds.

(c)

Interpretation Introduction

Interpretation:

Whether the side chain of amino acid Serine in plasma protein is found to be present on surface of the globular protein and in contact with aqueous environment or shielded from the aqueous environment has to be explained.

Concept Introduction:

Tendency of non-polar groups to cluster themselves and shield from the contact with an aqueous environment is known as Hydrophobic effect.  This effect plays an important role in folding of the polypeptide chain into three-dimensional shape. The nonpolar groups are excluded without interacting with molecules of water as water molecules stick through hydrogen bonding.  Hydrophilic side chains are the ones that interact with the aqueous environment by forming hydrogen bonds.

(d)

Interpretation Introduction

Interpretation:

Whether the side chain of amino acid Arginine in plasma protein is found to be present on surface of the globular protein and in contact with aqueous environment or shielded from the aqueous environment has to be explained.

Concept Introduction:

Tendency of non-polar groups to cluster themselves and shield from the contact with an aqueous environment is known as Hydrophobic effect.  This effect plays an important role in folding of the polypeptide chain into three-dimensional shape. The nonpolar groups are excluded without interacting with molecules of water as water molecules stick through hydrogen bonding.  Hydrophilic side chains are the ones that interact with the aqueous environment by forming hydrogen bonds.

(e)

Interpretation Introduction

Interpretation:

Whether the side chain of amino acid Phenylalanine in plasma protein is found to be present on surface of the globular protein and in contact with aqueous environment or shielded from the aqueous environment has to be explained.

Concept Introduction:

Tendency of non-polar groups to cluster themselves and shield from the contact with an aqueous environment is known as Hydrophobic effect.  This effect plays an important role in folding of the polypeptide chain into three-dimensional shape. The nonpolar groups are excluded without interacting with molecules of water as water molecules stick through hydrogen bonding.  Hydrophilic side chains are the ones that interact with the aqueous environment by forming hydrogen bonds.