Organic Chemistry - Standalone book
Organic Chemistry - Standalone book
10th Edition
ISBN: 9780073511214
Author: Francis A Carey Dr., Robert M. Giuliano
Publisher: McGraw-Hill Education
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Chapter 27, Problem 15P
Interpretation Introduction

Interpretation: The structure of 5-Fluorouracil has to be drawn.

Concept introduction: The compound 5-fluorouracil is used in the chemotherapy of breast-cancer. Uracil belongs to the class of pyrimidines. It is a nucleobase commonly found in RNA.

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Answer to Problem 15P

Solution:

The structure of 5-fluorouracil is shown below.

Organic Chemistry - Standalone book, Chapter 27, Problem 15P , additional homework tip  1

Explanation of Solution

The structure of uracil is shown below.

Organic Chemistry - Standalone book, Chapter 27, Problem 15P , additional homework tip  2

If a fluoro substituent is attached to the fifth position of the uracil ring, then the structure obtained is called 5-fluorouracil. The structure of 5-fluorouracil is shown below.

Organic Chemistry - Standalone book, Chapter 27, Problem 15P , additional homework tip  3

Conclusion

In the structure of 5-Fluorouracil, a fluoro substituent is attached to the fifth position of the uracil ring.

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