BIO 102 General Biology II Updated Edition (Tidewater Community College)
BIO 102 General Biology II Updated Edition (Tidewater Community College)
3rd Edition
ISBN: 9781259614064
Author: Tidewater Community College
Publisher: MCG CUSTOM
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Chapter 26.3, Problem 3MC
Summary Introduction

To determine:

The difference between graded potential, the threshold potential and action potential.

Concept introduction:

The membrane potential is defined as the difference in the concentration of ions on opposite sides of the cell membrane generates voltage across the membrane. It ranges from -40 mV to -70mV .

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Digoxin: Intravenous Bolus - Two Compartment Model Drug Digoxin Route: IV Bolus Dose: 0.750 mg Plasma Concentration Time Profile Beta Alpha Time (hrs) Conc (ng/ml) LN (ng/ml) LN (ng/ml) LN 0.00 #NUM! #NUM! #NUM! 0.10 12.290 2.509 #NUM! #NUMI 0.60 6.975 1.942 #NUM! #NUMI 1.00 4.649 1.537 #NUM! #NUMI 2.00 2.201 0.789 #NUM! #NUM! 3.00 1.536 0.429 #NUM! #NUM! 4.00 1.342 0.294 #NUM! #NUM! 5.00 1.273 0.241 #NUM! #NUMI 6.00 1.238 0.213 #NUM! #NUM! 7.00 1.212 0.192 #NUM! #NUM! 8.00 1.188 0.172 #NUMI #NUM! 9.00 1.165 0.153 #NUM! #NUMI 10.00 1.143 0.134 #NUMI #NUM! 11.00 1.122 0.115 #NUM! 12.00 1.101 0.096 #NUMI 13.00 1.080 0.077 #NUMI 16.00 1.020 0.020 #NUMI 24.00 0.876 -0.132 #NUMI Pharmacokinetic Parameters Parameter Value Alpha B Beta Units ng/ml hr-1 ng/ml hr-1 CO ng/ml H.C AUC ng x hr/ml Vc Vbeta Vss C L/hr TK (alpha) hr TX (beta) days 5+ F3 F4 F5 0+ F6 F7 % 6 95 14 #3 29 & t F8 F9 FW EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg rabbits following a bolus IV injection of 10mg/kg. Time (minutes) Serum Linuron Levels (ug/ml) following IV dose 10 15.48 20 8.60 30 5.90 45 3.78 60 2.42 90 1.49 120 0.93 180 0.60 240 0.41 300 0.29 360 0.22 Analyze this data and perform the necessary calculations to determine the following pharmacokinetic parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points possible). You do NOT need to submit graphs or data tables. Give the terminal regression line equation and R or R² value: Give the x axis (name and units, if any) of the terminal line: Give the y axis (name and units, if any) of the terminal line: Give the residual regression line equation and R or R² value: Give the x axis (name and units, if any) of the residual line: Give the y axis (name and units, if any) of the residual line:

Chapter 26 Solutions

BIO 102 General Biology II Updated Edition (Tidewater Community College)

Ch. 26.3 - Prob. 4MCCh. 26.3 - What prevents action potentials from spreading in...Ch. 26.3 - Prob. 6MCCh. 26.3 - How do myelin and the nodes of Ranvier speed...Ch. 26.4 - Describe the structure of a synapse.Ch. 26.4 - Prob. 2MCCh. 26.4 - Prob. 3MCCh. 26.4 - Prob. 4MCCh. 26.5 - Prob. 1MCCh. 26.5 - Prob. 2MCCh. 26.5 - Prob. 3MCCh. 26.5 - Prob. 4MCCh. 26.6 - Prob. 1MCCh. 26.6 - Prob. 2MCCh. 26.6 - Prob. 3MCCh. 26.6 - Prob. 4MCCh. 26.6 - Prob. 5MCCh. 26.6 - Prob. 6MCCh. 26.6 - List some structures that protect the central...Ch. 26.6 - Prob. 8MCCh. 26.6 - Prob. 9MCCh. 26.7 - 1. Use figure 26.22 to explain how saxitoxin...Ch. 26.7 - Prob. 2MCCh. 26 - Some cells of the central nervous system are...Ch. 26 - Prob. 2MCQCh. 26 - What event triggers an action potential? a....Ch. 26 - Prob. 4MCQCh. 26 - Prob. 5MCQCh. 26 - Damage to the surface tissue of the spinal cord...Ch. 26 - Prob. 7MCQCh. 26 - Describe some invertebrate nervous systems. Why do...Ch. 26 - Prob. 2WIOCh. 26 - Prob. 3WIOCh. 26 - Prob. 4WIOCh. 26 - Write a nonbiological analogy for resting...Ch. 26 - Prob. 6WIOCh. 26 - Prob. 7WIOCh. 26 - Sketch a synapse: label the axon and synaptic...Ch. 26 - Prob. 9WIOCh. 26 - Prob. 10WIOCh. 26 - Prob. 11WIOCh. 26 - Prob. 12WIOCh. 26 - Prob. 13WIOCh. 26 - Cerebral palsy is a nervous system disorder that...Ch. 26 - Traumatic brain injury can occur when a person...Ch. 26 - Prob. 16WIOCh. 26 - Prob. 17WIOCh. 26 - Prob. 18WIOCh. 26 - Prob. 19WIOCh. 26 - Prob. 1PITCh. 26 - Prob. 2PITCh. 26 - Prob. 3PITCh. 26 - PULL IT TOGETHER 4. Acid the somatic, autonomic,...
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