Nester's Microbiology: A Human Perspective
Nester's Microbiology: A Human Perspective
8th Edition
ISBN: 9780073522593
Author: Denise G. Anderson Lecturer, Sarah Salm, Deborah Allen
Publisher: McGraw-Hill Education
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Chapter 26, Problem 2MC
Summary Introduction

Introduction:

Listeriosis, a foodborne disease is caused by Listeria monocytogenes(L. monocytogenes). This disease is generally asymptomaticin healthy individuals. However, its symptoms are muscles aches, fever, fatigue, anddiarrhea. It causes the onset of meningitis. Ingested L. monocytogenes can penetrate into the mucosal intestinal linings and get penetrated into the bloodstream and cause meningitis. This disease can be caused by food contaminated with L. monocytogenes.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
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