Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
Question
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Chapter 26, Problem 1P
Interpretation Introduction

Interpretation: The correct option by which all glycerol containing phospholipids are derived should be determined.

Concept Introduction: Phospholipids are the basic constituent of all cell membranes. They usually form lipid bilayers. The structure of a phospholipid molecule has a tail made up of two hydrophobic fatty acid and a hydrophilic head comprising of a phosphate group.

Expert Solution & Answer
Check Mark

Answer to Problem 1P

Correct answer: option (d) Phosphatidate.

Explanation of Solution

Reason for correct option:

Option (d) Phosphatidate. Phosphatidate is formed during the initial step of the production of both triacylglycerols for energy storage and phospholipids for membranes. These molecules are lipids. The initial two carbon atoms of the glycerol unit in phosphatidate are fatty acid esters. While the third carbon atom is a phosphate ester. This phosphate facilitates a connection with another alcohol such as serine, choline, ethanolamine, or a carbohydrate. Hence, this option is correct.

Conclusion

Reasons for incorrect options:

Option (a) Ceramide. Ceramides are a class of waxy lipid molecules. These are composed of sphingosine and a fatty acid. These are present in high concentrations inside the eukaryotic cell membrane. Hence, this option is incorrect.

Option (b) Ganglioside. These are a group of complex lipids. These are present in the grey matter of the human brain. Hence, this option is incorrect.

Option (c) Mevalonate. Mevalonic acid or MVA is an important organic compound in biochemistry. The MVA pathway help in the biosynthesis of isoprenoids from acetate. Hence, this option is incorrect.

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