Chapter 26, Problem 104P

Interpretation Introduction

Interpretation:

To explain why does the loss of CO₂ make the citric acid cycle irreversible.

Concept introduction:

The citric acid cycle or the tricarboxylic acid cycle (TCA cycle) or Krebs cycle is a string of chemical reactions utilized by all the aerobic organisms to liberate the stored energy via oxidation of acetyl-CoA obtained from carbohydrates, fats, and proteins into ATP and carbon dioxide. Besides, the TCA cycle supplies the precursors of a few amino acids, and reducing agent NADH, which are utilized in many other reactions.