Organic Chemistry
12th Edition
ISBN: 9781118875766
Author: T. W. Graham Solomons, Craig B. Fryhle, Scott A. Snyder
Publisher: WILEY
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Chapter 25, Problem 8PP
Interpretation Introduction
Interpretation:
The intermediate formed during the conversion of adenine to hypoxanthine, hydrogen bonds of hypoxanthine-cytosine base pair and the consequences it would have through two rounds of DNA (deoxyribonucleic acid) replication is to be shown.
Concept Introduction:
▸ Normally, in DNA, adenine pairs with thymine by forming two hydrogen bonds. On treatment with nitrous acid, amino group of adenine undergoes changes to form diazonium and finally gets removed.
▸ Hypoxanthine forms two hydrogen bonds with cytosine instead of thymine. This mispairing then passes on to the daughter DNA formed during replication and further brings about permanent changes (mutations).
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Chapter 25 Solutions
Organic Chemistry
Ch. 25 - Prob. 1PPCh. 25 - Prob. 2PPCh. 25 - Prob. 3PPCh. 25 - Prob. 4PPCh. 25 - Prob. 5PPCh. 25 - Practice Problem 25.6 (a) There are approximately...Ch. 25 - Prob. 7PPCh. 25 - Prob. 8PPCh. 25 - Prob. 9PPCh. 25 - Practice Problem 25.10
The sense strand of a...
Ch. 25 - Practice Problem 25.11
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