GENERAL,ORGANIC, & BIOLOGICAL CHEM-ACCES
4th Edition
ISBN: 9781265982959
Author: SMITH
Publisher: MCG
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Chapter 25, Problem 46P
Interpretation Introduction
Interpretation:
The reason should be determined for the ability of nicotine to cross the blood-brain barrier.
Concept Introduction:
Nicotine is a chemical that is obtained from the tobacco plant. In minute quantities, it is known to act as a stimulant but when it exceeds a certain limit it has very adverse effects. It is one of the molecules which is known to gain entry through the blood-brain barrier.
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The SN 1 mechanism starts with the rate-determining step which is the dissociation of the alkyl halide into a carbocation and a halide ion. The next step is
the rapid reaction of the carbocation intermediate with the nucleophile; this step completes the nucleophilic substitution stage. The step that follows the
nucleophilic substitution is a fast acid-base reaction. The nucleophile now acts as a base to remove the proton from the oxonium ion from the previous
step, to give the observed product. Draw a curved arrow mechanism for the reaction, adding steps as necessary. Be sure to include all nonzero formal
charges.
Cl:
Add/Remove step
G
Click and drag to start
drawing a structure.
Please correct answer and don't use hand rating
Chapter 25 Solutions
GENERAL,ORGANIC, & BIOLOGICAL CHEM-ACCES
Ch. 25.1 - Prob. 25.1PCh. 25.1 - Prob. 25.2PCh. 25.2 - Compare erythrocytes, leukocytes, and platelets...Ch. 25.2 - Prob. 25.4PCh. 25.2 - Prob. 25.5PCh. 25.2 - Prob. 25.6PCh. 25.2 - Prob. 25.7PCh. 25.3 - Prob. 25.8PCh. 25.3 - Prob. 25.1PPCh. 25.3 - Prob. 25.9P
Ch. 25.3 - Prob. 25.10PCh. 25.4 - Prob. 25.11PCh. 25.4 - Prob. 25.12PCh. 25.5 - (a) Which compound, morphine or heroin, is more...Ch. 25.5 - Prob. 25.14PCh. 25.6 - Prob. 25.15PCh. 25.6 - Prob. 25.16PCh. 25.6 - Prob. 25.17PCh. 25.6 - Individuals with a rare condition called diabetes...Ch. 25 - Prob. 19PCh. 25 - Prob. 20PCh. 25 - Prob. 21PCh. 25 - Prob. 22PCh. 25 - Prob. 23PCh. 25 - Prob. 24PCh. 25 - Prob. 25PCh. 25 - Prob. 26PCh. 25 - For each substance, indicate if it is present in...Ch. 25 - Prob. 28PCh. 25 - Prob. 29PCh. 25 - Prob. 30PCh. 25 - Prob. 31PCh. 25 - Prob. 32PCh. 25 - Prob. 33PCh. 25 - Prob. 34PCh. 25 - Prob. 35PCh. 25 - Which of the following locations corresponds to...Ch. 25 - Prob. 37PCh. 25 - Prob. 38PCh. 25 - Prob. 39PCh. 25 - Prob. 40PCh. 25 - Prob. 41PCh. 25 - Prob. 42PCh. 25 - Explain how abnormally fast respirationthat is,...Ch. 25 - Prob. 44PCh. 25 - Prob. 45PCh. 25 - Prob. 46PCh. 25 - Prob. 47PCh. 25 - Prob. 48PCh. 25 - When blood flows through the glomerulus, which...Ch. 25 - Prob. 50PCh. 25 - Prob. 51PCh. 25 - Prob. 52P
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