Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
Question
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Chapter 25, Problem 46P
Interpretation Introduction

(a)

Interpretation:

The reason for the beneficial effects of ADP to ATP and AMP should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(b)

Interpretation:

The equilibrium constant for adenylate kinase is 1. The reason for this is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(c)

Interpretation:

The reason for the facilitation of ATP synthesis due to AMP deamination, should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(d)

Interpretation:

The way by which ATP is synthesized aerobically due to the purine nucleotide cycle, is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

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