Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 25, Problem 27P
Interpretation Introduction

Interpretation:

Possible treatment for orotic aciduria is to be determined.

Concept introduction:

Orotic aciduria is a disease caused due to the deficiency of UMP synthetase enzyme. The function of this enzyme is to convert orotic acid into UMP (uridine monophosphate). This means, inactivity of the enzyme results in a decreased ability of synthesis of pyrimidines.

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