(a) Interpretation: The reason for the beneficial effects of ADP to ATP and AMP should be determined. Concept introduction: The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Question

Want to see the full answer?

Answer 1

Question

Chapter 25, Problem 41P

Interpretation Introduction

(a)

Interpretation:

The reason for the beneficial effects of ADP to ATP and AMP should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(b)

Interpretation:

The equilibrium constant for adenylate kinase is 1. The reason for this is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(c)

Interpretation:

The reason for the facilitation of ATP synthesis due to AMP deamination, should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(d)

Interpretation:

The way by which ATP is synthesized aerobically due to the purine nucleotide cycle, is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Pyruvate is accepted into the TCA cycle by a “feeder” reaction using the pyruvatedehydrogenase complex, resulting in acetyl-CoA and CO2. Provide a full mechanismfor this reaction utilizing the TPP cofactor. Include the roles of all cofactors.

B- Vitamins are converted readily into important metabolic cofactors. Deficiency inany one of them has serious side effects. a. The disease beriberi results from a vitamin B 1 (Thiamine) deficiency and ischaracterized by cardiac and neurological symptoms. One key diagnostic forthis disease is an increased level of pyruvate and α-ketoglutarate in thebloodstream. How does this vitamin deficiency lead to increased serumlevels of these factors? b. What would you expect the effect on the TCA intermediates for a patientsuffering from vitamin B 5 deficiency? c. What would you expect the effect on the TCA intermediates for a patientsuffering from vitamin B 2 /B 3 deficiency?

Draw the Krebs Cycle and show the entry points for the amino acids Alanine,Glutamic Acid, Asparagine, and Valine into the Krebs Cycle - (Draw the Mechanism). How many rounds of Krebs will be required to waste all Carbons of Glutamic Acidas CO2?

Answer 2

Question

Chapter 25, Problem 41P

Interpretation Introduction

(a)

Interpretation:

The reason for the beneficial effects of ADP to ATP and AMP should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(b)

Interpretation:

The equilibrium constant for adenylate kinase is 1. The reason for this is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(c)

Interpretation:

The reason for the facilitation of ATP synthesis due to AMP deamination, should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(d)

Interpretation:

The way by which ATP is synthesized aerobically due to the purine nucleotide cycle, is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 25, Problem 41P

Interpretation Introduction

(a)

Interpretation:

The reason for the beneficial effects of ADP to ATP and AMP should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(b)

Interpretation:

The equilibrium constant for adenylate kinase is 1. The reason for this is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(c)

Interpretation:

The reason for the facilitation of ATP synthesis due to AMP deamination, should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(d)

Interpretation:

The way by which ATP is synthesized aerobically due to the purine nucleotide cycle, is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 25, Problem 41P

Interpretation Introduction

(a)

Interpretation:

The reason for the beneficial effects of ADP to ATP and AMP should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(b)

Interpretation:

The equilibrium constant for adenylate kinase is 1. The reason for this is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(c)

Interpretation:

The reason for the facilitation of ATP synthesis due to AMP deamination, should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(d)

Interpretation:

The way by which ATP is synthesized aerobically due to the purine nucleotide cycle, is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 25, Problem 41P

Interpretation Introduction

(a)

Interpretation:

The reason for the beneficial effects of ADP to ATP and AMP should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(b)

Interpretation:

The equilibrium constant for adenylate kinase is 1. The reason for this is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(c)

Interpretation:

The reason for the facilitation of ATP synthesis due to AMP deamination, should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Interpretation Introduction

(d)

Interpretation:

The way by which ATP is synthesized aerobically due to the purine nucleotide cycle, is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Answer 6

Chapter 25, Problem 41P

Interpretation Introduction

(a)

Interpretation:

The reason for the beneficial effects of ADP to ATP and AMP should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Answer 7

Chapter 25, Problem 41P

Interpretation Introduction

(a)

Interpretation:

The reason for the beneficial effects of ADP to ATP and AMP should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Answer 8

Interpretation Introduction

(b)

Interpretation:

The equilibrium constant for adenylate kinase is 1. The reason for this is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Answer 9

Interpretation Introduction

(b)

Interpretation:

The equilibrium constant for adenylate kinase is 1. The reason for this is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Answer 10

Interpretation Introduction

(c)

Interpretation:

The reason for the facilitation of ATP synthesis due to AMP deamination, should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Answer 11

Interpretation Introduction

(c)

Interpretation:

The reason for the facilitation of ATP synthesis due to AMP deamination, should be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Answer 12

Interpretation Introduction

(d)

Interpretation:

The way by which ATP is synthesized aerobically due to the purine nucleotide cycle, is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Answer 13

Interpretation Introduction

(d)

Interpretation:

The way by which ATP is synthesized aerobically due to the purine nucleotide cycle, is to be determined.

Concept introduction:

The purine nucleotide cycle is a metabolic process, in which aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine nucleotides. This cycle is comprised of three biochemical reactions, deamination of AMP to IMP, the formation of adenylosuccinate from IMP, and conversion of adenylosuccinate to AMP and fumarate.

Answer 14

Expert Solution & Answer

Answer 15

Expert Solution & Answer

Answer 16

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 17

Ch. 25 - Prob. 1P Ch. 25 - Prob. 2P Ch. 25 - Prob. 3P Ch. 25 - Prob. 4P Ch. 25 - Prob. 5P Ch. 25 - Prob. 6P Ch. 25 - Prob. 7P Ch. 25 - Prob. 8P Ch. 25 - Prob. 9P Ch. 25 - Prob. 10P

Solution Summary: The author explains the purine nucleotide cycle, where aspartate and IMP are converted into ammonia and fumarate to regulate the levels of adenine.

Want to see the full answer?

Chapter 25 Solutions