BIOCHEMISTRY
BIOCHEMISTRY
9th Edition
ISBN: 2818440090622
Author: BERG
Publisher: MAC HIGHER
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Chapter 25, Problem 38P
Interpretation Introduction

Interpretation:

Biosynthetic pathways are to be determined, in which PRPP is utilized.

Concept introduction:

Phosphoribosyl pyrophosphate (PRPP) is a pentosephosphate, which is synthesized from ribose-5-phosphate by the catalytic action of ribose-phosphate diphosphokinase. The high amount of PRPP leads to the accumulation of uric acid, causing hyperuricemia. This is one of the reasons for gout formation.

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