BIOCHEM. II-EBOOK ACCESS>CUSTOM<
BIOCHEM. II-EBOOK ACCESS>CUSTOM<
18th Edition
ISBN: 9781337700320
Author: GARRETT
Publisher: CENGAGE LEARNING (CUSTOM)
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Chapter 25, Problem 22P
Interpretation Introduction

Interpretation:

The double-displacement (ping-pong) catalytic mechanism needs to be determined for the glutamate oxaloacetate transaminase I.

Concept Introduction:

A double displacement reaction follows a bimolecular mechanism. In the mechanism, two reactants say XY and MN reacts to form XM and YN product. This is due to the nucleophilic attack of 1 group on another which results in the release of groups to form new compound. The enzymatic double displacement reaction is also known as ping-pong reaction. It takes place when 1 or more products are formed before the binding of all substrate to the enzyme.

In the mechanism, the substrate bounces on and off the enzyme like a ping pong ball.

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9. Which one of the compounds below is the major organic product obtained from the following reaction sequence, starting with ethyl acetoacetate? 요요. 1. NaOCH2CH3 CH3CH2OH 1. NaOH, H₂O 2. H3O+ 3. A OCH2CH3 2. ethyl acetoacetate ii A 3. H3O+ OH B C D E
7. Only one of the following ketones cannot be made via an acetoacetic ester synthesis. Which one is it? Ph کہ A B C D E
2. Which one is the major organic product obtained from the following reaction sequence? HO A OH 1. NaOEt, EtOH 1. LiAlH4 EtO OEt 2. H3O+ 2. H3O+ OH B OH OH C -OH HO -OH OH D E .CO₂Et
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