INTRO.TO GENERAL,ORGAN...-OWLV2 ACCESS
12th Edition
ISBN: 9781337915977
Author: Bettelheim
Publisher: CENGAGE L
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Textbook Question
Chapter 24.2, Problem 24.1QC
Problem 25-1
Draw the structure of UMP.
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need help please and thanks dont understand only need help with C-F
Learning Goal:
As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.
The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).
Part A - Difference in binding free eenergies
Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol.
The margin of error is 2%.
Part B - Compare difference in free energy to the thermal…
Please correct answer and don't used hand raiting
need help please and thanks dont understand a-b
Learning Goal:
As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.
The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).
Part A - Difference in binding free eenergies
Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol.
The margin of error is 2%.
Part B - Compare difference in free energy to the thermal energy
Divide the…
Chapter 24 Solutions
INTRO.TO GENERAL,ORGAN...-OWLV2 ACCESS
Ch. 24.2 - Problem 25-1 Draw the structure of UMP.Ch. 24.3 - Prob. 24.2QCCh. 24.3 - Prob. 24.3QCCh. 24.4 - Prob. 24.4QCCh. 24.5 - Prob. 24.5QCCh. 24.6 - Prob. 24.6QCCh. 24.7 - Prob. 24.7QCCh. 24.8 - Prob. 24.8QCCh. 24 - Prob. 1PCh. 24 - 25-2 What structures Of the cell, visible in a...
Ch. 24 - 25-3 Name one hereditary disease.Ch. 24 - 25-4 What is the basis unit of heredity?Ch. 24 - 25-5 (a) Where in a cell is the DNA located? (b)...Ch. 24 - 25-6 What are the components of (a) a nucleotide...Ch. 24 - 25-7 What are the differences between DNA and RNA?Ch. 24 - 25-8 Draw the structures of ADP and GDP. Are these...Ch. 24 - Prob. 9PCh. 24 - 25-10 Which DNA and RNA bases contain a carbonyl...Ch. 24 - Prob. 11PCh. 24 - Prob. 12PCh. 24 - Prob. 13PCh. 24 - Prob. 14PCh. 24 - Prob. 15PCh. 24 - Prob. 16PCh. 24 - Prob. 17PCh. 24 - 25-18 What type of bond connects the base to the...Ch. 24 - Prob. 19PCh. 24 - 25-20 What constitutes the backbone of DNA?Ch. 24 - Prob. 21PCh. 24 - 25-22 In DNA, which carbon atoms of...Ch. 24 - 25-23 The sequence Of a short DNA segment is...Ch. 24 - Prob. 24PCh. 24 - Prob. 25PCh. 24 - Prob. 26PCh. 24 - Prob. 27PCh. 24 - Prob. 28PCh. 24 - 25-29 What constitutes the superstructure of...Ch. 24 - 25-30 What is the primary structure of DNA?Ch. 24 - 25-31 What is the secondary structure of DNA?Ch. 24 - 25-32 What is the major groove of a DNA helix?Ch. 24 - 25-33 What are the higher-order structures of DNA...Ch. 24 - 25-34 Which type Of RNA has enzyme activity? Where...Ch. 24 - 25-35 Which has the longest chains: tRNA, mRNA, or...Ch. 24 - 25-36 Which type of RNA contains modified...Ch. 24 - 25-37 Which type Of RNA has a sequence exactly...Ch. 24 - 25-38 Where is rRNA located in the cell?Ch. 24 - Prob. 39PCh. 24 - Prob. 40PCh. 24 - Prob. 41PCh. 24 - Prob. 42PCh. 24 - Prob. 43PCh. 24 - 25-50 Define: (a) Intron (b) ExonCh. 24 - 25-51 Does mRNA also have introns and exons?...Ch. 24 - Prob. 46PCh. 24 - Prob. 47PCh. 24 - 25-54 Do all genes code for a protein? If not,...Ch. 24 - Prob. 49PCh. 24 - Prob. 50PCh. 24 - Prob. 51PCh. 24 - Prob. 52PCh. 24 - Prob. 53PCh. 24 - Prob. 54PCh. 24 - Prob. 55PCh. 24 - Prob. 56PCh. 24 - 25-55 A DNA molecule normally replicates itself...Ch. 24 - 25-56 Which functional groups on the bases form...Ch. 24 - Prob. 59PCh. 24 - 25-58 Draw the structures of cytosine and guanine...Ch. 24 - 25-59 How many different bases are present in a...Ch. 24 - Prob. 62PCh. 24 - 25-61 Why is replication called semiconservative?Ch. 24 - 25-62 How does the removal of some positive...Ch. 24 - 25-63 Write the chemical reaction for the...Ch. 24 - Prob. 66PCh. 24 - 25-65 What are helicases? What is their function?Ch. 24 - 25-66 Can dATP Serve as a source for a primer?Ch. 24 - Prob. 69PCh. 24 - Prob. 70PCh. 24 - 25-69 In which direction is the DNA molecule...Ch. 24 - Prob. 72PCh. 24 - Prob. 73PCh. 24 - Prob. 74PCh. 24 - 25-73 From the perspective of the chain being...Ch. 24 - Prob. 76PCh. 24 - Prob. 77PCh. 24 - Prob. 78PCh. 24 - Prob. 79PCh. 24 - Prob. 80PCh. 24 - Prob. 81PCh. 24 - Prob. 82PCh. 24 - Prob. 83PCh. 24 - Prob. 84PCh. 24 - Prob. 85PCh. 24 - Prob. 86PCh. 24 - Prob. 87PCh. 24 - Prob. 88PCh. 24 - Prob. 89PCh. 24 - Prob. 90PCh. 24 - Prob. 91PCh. 24 - Prob. 92PCh. 24 - Prob. 93PCh. 24 - (Chemical Connections 24E) What gene associated...Ch. 24 - Prob. 95PCh. 24 - -104 Why is it important that a DNA molecule be...Ch. 24 - Prob. 97PCh. 24 - Prob. 98PCh. 24 - Prob. 99PCh. 24 - Prob. 100PCh. 24 - -109 In sheep DNA, the mol% of adenine (A) was...Ch. 24 - Prob. 102PCh. 24 - Prob. 103PCh. 24 - Prob. 104PCh. 24 - Prob. 105PCh. 24 - -114 How could life have evolved if DNA leads to...Ch. 24 - Prob. 107PCh. 24 - Prob. 108PCh. 24 - Prob. 109P
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