MOLECULAR BIOLOGY OF THE CELL (LL)
6th Edition
ISBN: 9780393876109
Author: ALBERTS
Publisher: NORTON
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Chapter 24, Problem 8P
A.
Summary Introduction
To explain: Cytotoxic T cells having heterozygous d-type/k-type class I MHC can lyse infected d-type cells and k-type cells or not.
Concept introduction: T cells and B cells are lymphocytes of the immune system which helps to elicit an immune response against an invading pathogen. T cells are antigen-presenting cells (APC). There are three types of T cells: Cytotoxic T cells, Helper T cells and memory T cells. There are other minor types of T cells like natural killer T cell, γδ T cells and many more. The main function of cytotoxic T cells represented as TC have T-cell receptors on the surface of their plasma membrane that has the capacity to recognize specific antigens that can be even nuclear proteins of the pathogen.
B.
Summary Introduction
To explain: Nude mouse which has cytotoxic T cells having heterozygous d-type /k-type was given a thymus from an d-type donor will lyse d-type infected cells or k-type infected cells or neither.
Concept introduction: T cells and B cells are lymphocytes of the immune system which helps to elicit an immune response against an invading pathogen. T cells are antigen-presenting cells (APC). There are three types of T cells: Cytotoxic T cells, Helper T cells and memory T cells. There are other minor types of T cells like natural killer T cell, γδ T cells and many more. The main function of cytotoxic T cells represented as TC have T-cell receptors on the surface of their plasma membrane that has the capacity to recognize specific antigens that can be even nuclear proteins of the pathogen.
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