MOLECULAR BIOLOGY OF THE CELL (LL)
MOLECULAR BIOLOGY OF THE CELL (LL)
6th Edition
ISBN: 9780393876109
Author: ALBERTS
Publisher: NORTON
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Chapter 24, Problem 3P
Summary Introduction

To examine: Whether the statement, “The antibody diversity created by the combinatorial joining of V, D, and J segments by V(D)J recombination pales in comparison to the enormous diversity created by the random gain and loss of nucleotides at V, D, and J joining sites”, is true or false.

Introduction: V(D)J recombination occurs in the bone marrow during early developmental stages where the developing T and B lymphocytes undergo recombination. This recombination results in loss or gain of genes. The genetic recombination results in antibody diversity by generating diverse heavy and light chains of the immunoglobulins.

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