Human Anatomy & Physiology
1st Edition
ISBN: 9780805382952
Author: Erin C. Amerman
Publisher: PEARSON
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Chapter 24, Problem 3AYKA
Deana is a 4-year-old girl with a rare genetic defect that causes the Na+/glucose symporters in the proximal tubule to reabsorb fewer glucose and sodium ions than normal. Predict the effects this defect will have on the composition and volume of Deana’s urine. Explain why you would expect to see increased activity of the tubuloglomerular feedback and the renin-angiotensin-aldosterone system in Deana’s kidneys.
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Chapter 24 Solutions
Human Anatomy & Physiology
Ch. 24.1 - What are the organs of the urinary system?Ch. 24.1 - 2. What are the basic functions of the kidneys?
Ch. 24.2 - Prob. 1QCCh. 24.2 - 2. What are the three regions of the kidney, and...Ch. 24.2 - Prob. 3QCCh. 24.2 - Trace the sequence of blood flow through the...Ch. 24.2 - Prob. 5QCCh. 24.2 - Prob. 6QCCh. 24.2 - Trace the pathway filtrate takes through the...Ch. 24.3 - Prob. 1QC
Ch. 24.3 - 2. How do tubular reabsorption and tubular...Ch. 24.4 - Prob. 1QCCh. 24.4 - Prob. 2QCCh. 24.4 - Prob. 3QCCh. 24.4 - 4. What is the GFR?
Ch. 24.4 - Prob. 5QCCh. 24.4 - Prob. 6QCCh. 24.4 - 7. How does tubuloglomerular feedback affect the...Ch. 24.4 - Prob. 8QCCh. 24.4 - Prob. 9QCCh. 24.4 - Prob. 10QCCh. 24.4 - How does the sympathetic nervous system affect the...Ch. 24.5 - Prob. 1QCCh. 24.5 - Prob. 2QCCh. 24.5 - Prob. 3QCCh. 24.5 - What is obligatory water reabsorption?Ch. 24.5 - How do the permeabilities of the two limbs of the...Ch. 24.5 - Prob. 6QCCh. 24.5 - Prob. 7QCCh. 24.5 - Prob. 8QCCh. 24.6 - Prob. 1QCCh. 24.6 - Prob. 2QCCh. 24.6 - Prob. 3QCCh. 24.6 - Prob. 4QCCh. 24.6 - 5. What three factors allow the kidney to produce...Ch. 24.6 - 6. How is concentrated urine produced?
Ch. 24.8 - 1. What is the normal composition of urine?
Ch. 24.8 - Prob. 2QCCh. 24.8 - 3. What is renal clearance, and what is it used...Ch. 24.9 - Prob. 1QCCh. 24.9 - 2. What are the functions of the ureters and...Ch. 24.9 - Prob. 3QCCh. 24.9 - Prob. 4QCCh. 24.9 - Prob. 5QCCh. 24 - What are the four main organs of the urinary...Ch. 24 - 2. Which of the following is not a physiological...Ch. 24 - Mark the following statements as true or false. If...Ch. 24 - Prob. 4CYRCh. 24 - Prob. 5CYRCh. 24 - Which of the following substances would pass...Ch. 24 -
7. Fill in the blanks: Glomerular hydrostatic...Ch. 24 - Fill in the blanks for the following statements:...Ch. 24 - Which of the following is false about the GFR? a....Ch. 24 - The route by which substances are reabsorbed by...Ch. 24 -
11. Mark the following statements as true or...Ch. 24 - Dilute urine is produced when decreased levels of...Ch. 24 - Prob. 13CYRCh. 24 - Prob. 14CYRCh. 24 - Prob. 15CYRCh. 24 - 16. The GFR may be estimated by measuring the rate...Ch. 24 - Prob. 17CYRCh. 24 - Prob. 1CYUCh. 24 - Prob. 2CYUCh. 24 - Prob. 3CYUCh. 24 - Why must the kidneys establish a concentration...Ch. 24 - 1. Drugs that treat hypertension, or high blood...Ch. 24 - Prob. 2AYKACh. 24 - 3. Deana is a 4-year-old girl with a rare genetic...Ch. 24 - 4. Explain how each of the drugs in question 1...Ch. 24 - 5. What might it mean if you found a high...
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- As the text noted, two-thirds of the water and solutes that the body reclaims by reabsorption in nephrons occurs in the proximal tubule. Proximal tubule cells have large numbers of mitochondria and demand a great deal of oxygen. Explain why.arrow_forwardWhich of the following does not contribute to the high salt concentration in the interstitial fluid of the kidney medulla? (a) active transport of sodium from the upper part of the ascending limb (b) diffusion of salt from the ascending limb of the loop of Henle (c) reabsorption of salt from various regions of Bowmans capsule (d) counterflow of fluid through the two limbs of the loop of Henle (e) diffusion of urea out of the collecting ductarrow_forwardWhich of the following does not contribute to the process of filtration? (a) active transport by epithelial cells lining renal tubules (b) large surface area for filtration (c) low permeability of glomerular capillaries (d) high hydrostatic blood pressure in glomerular capillaries (e) podocytesarrow_forward
- Which is TRUE of the RAAS pathway? angiotensin Il directly leads to vasoconstriction and stimulates aldosterone which promotes Na+ reabsorption at the cortical collecting duct ANP stimulates the RAAS pathway, while ADH/vasopressin inhibits the RAAS pathway increased plasma volume directly puts extra pressure on the afferent arteriole and indirectly increases pressure in the distal tubule, both of which lead to stimulation of renin release angiotensin Il promotes activation of the parasympathetic system which decreases GFR low plasma Na+ is sensed by the proximal tubule and triggers release of renin from JGA cellsarrow_forwardAcetazolamide is a diuretic that blocks the activity of the enzyme carbonic anhydrase inside kidney tubule cells. This blockage prevents theformation of carbonic acid from CO2 and water. Normally, carbonicacid dissociates to form H+ and HCO3−, and the H+ is exchanged forNa+ from the urine. Blocking the formation of H+ in the tubule cellsblocks Na+ reabsorption, thus inhibiting water reabsorption andproducing the diuretic effect. With this information in mind, what effectdoes acetazolamide have on blood pH, urine pH, and respiratory rate?arrow_forwardMaria is 8 months pregnant. When she goes to her doctor for her checkup, the nurse takes her blood pressure. It is unusually high: 200/100 mm Hg. The nurse also collects a urine sample and detects elevated levels of protein in her urine.What do you think has happened to her urine production? (Consider the pressures involved in determining net filtration pressure and osmotic force generated by solutes in the filtrate.) a. Urine production has stayed the same. b. Urine production has increased. c. Urine production has decreased. d. It is not possible to predict the effect on urine production.arrow_forward
- All of the following are true about glucose recovery from the tubule fluid, except (choose the incorrect statement): A. All filtered glucose is released in the PCT unless plasma glucose abnormally high B. It is reabsorbed by coupling with Na+ recovery via a sodium glucose cotransporter C. Glucose recovery is made possible by low intracellular Na+ concentrations created by the NaK pump D. The CD recovers any glucose that is not reabsorbed by the PCT nephron loop and DCT this is not and will not be gradedarrow_forwardA patient comes to your medical practice with complaints of low urine output (not peeing). You use inulin to calculate the glomerular filtration rate (GFR) using the following information: Plasma level (P – constant over 24 hours): 10 mg/mL inulin. Urine sample (U): 144 mg inulin/mL urine. Urine formation (V): 10 mL/min. Using the fromula GFR=V ✕ U/P, you calculate a GFR of ... A) 144mL/min.. B) 14400 mL/min. C) 144 min./mL. D) 144 g mannitol/min.arrow_forwardAlthough the kidneys are probably best known as filtration organs, tubular reabsorption (the second step of urine formation in a nephron) actually reclaims molecules that have already been filtered from the blood. Describe the tubular reabsorption process, including the structures and molecules involved, and explain why these molecules need to be reabsorbed. please helparrow_forward
- In the condition diabetes mellitus, why does glucose appear in the urine? Group of answer choices The plasma concentration of glucose becomes so high that it diffuses from peritubular capillaries into the proximal tubule, down its concentration gradient. The filtered load of glucose becomes greater than the tubular maximum for its reabsorption. Without the hormone insulin, glucose cannot enter proximal tubule epithelial cells. The rate of tubular secretion of glucose becomes greater than the sum of glucose filtration and reabsorption.arrow_forwardUnder circumstances of having low blood pressure , how does the sympathetic nervous system decrease glomerular filtration rate ? stimulates constriction of the efferent arteriole only stimulates relaxation of the mesangial cells stimulates secretion of erythropoietin stimulates constriction of both the afferent and efferent arteriolesarrow_forwardWhich of the following changes will occur as a result of elevated mean arterial blood pressure? Answers A - E A Increased resistance of the efferent arteriole B Decreased NaCl excretion C Docreased renin release D The macula densa will stimulate the juxtaglomerular cells E Increased aldosterone releasearrow_forward
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