Developmental Biology
11th Edition
ISBN: 9781605354705
Author: Scott F. Gilbert, Michael J. F. Barresi
Publisher: Sinauer Associates is an imprint of Oxford University Press
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Chapter 24, Problem 2DQ
Summary Introduction
To review:
The possible cause for the malformation (six or more limbs) in frogs found in certain ponds of northen united states.
Introduction:
Retinoic acid is a vitamin A derivative which play an important role in specifying the anterior posterior axis and essential for the normal growth and development in chordates. But sometime a compound required for the normal growth and development may cause deleterious effects when present in large or inappropriate quantities. The abnormal limb development in the frogs of northen united states also associated with the increase in retinoic acid in frog limb buds following the frog association with a
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