Chapter 24, Problem 18TE

How might the structure of benzocaine be modified to create a compound having greater anesthetic properties?

To determine

The method to enhance the anesthetic properties by modification of structure of benzocaine.

Answer to Problem 18TE

By the substitution of the amine group in the end chain of benzocaine, the anesthetic properties can be modified.

Explanation of Solution

Anesthetic drugs are those medicinal drugs which are injected either through syringe or orally (in gaseous phase) in order to numb selective region in the human body. The numbness in the human body helps the patient to undergo any painful treatment without any feeling or sensation of pain. The receptors responsible for the pain are inactivated by the presence of anesthesia. Anesthesia is consisting of three part – aromatic rings, intermediate chain and the end amine group. Benzocaine can be modified chemically to redevelop drug local anesthesia depending upon the effect required for treatment.

Conclusion:

Therefore, by the substitution of the amine group in the end chain of benzocaine, the anesthetic properties can be modified.