
To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered as the gain-of-function mutations.
Introduction: Cancer is caused when one of the alleles of an oncogene is mutated or both the alleles of tumor suppressor genes are mutated. The mutation in both genes affects the expression of these genes, which affects the regulation of the cell cycle.
To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered the loss-of-function mutations.
Introduction: When the genes of somatic cells are mutated, they are not passed to the next generation. Therefore, cancer is not inherited. When a mutation occurs in germ cells, then it makes cancer, inherited.

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Chapter 24 Solutions
Concepts of Genetics (12th Edition)
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