Chapter 23, Problem 72CP

(a)

Interpretation Introduction

Interpretation:

The product of the reaction has to be identified.

Concept Introduction:

Suzuki reaction: It involves coupling of an aryl, a benzyl or vinyl halide with organoborane in presence of palladium catalyst which is indicated as follows,

  $\begin{array}{l}{\text{R}}_{\text{1}}{\text{-BY}}_{\text{2}}{\text{+R}}_{\text{2}}\text{-X}\underset{Base}{\overset{Pdcatalyst}{\to }}{\text{R}}_{\text{1}}{\text{-R}}_{\text{2}}\\ Here{\text{R}}_{\text{1}}{\text{-BY}}_{\text{2}}\Rightarrow Organoboron\\ {\text{R}}_{\text{2}}\text{-X}\Rightarrow Organohalide\\ {\text{R}}_{\text{1}}{\text{-R}}_{\text{2}}\Rightarrow resultingcoupledproduct\end{array}$

Stille coupling reaction: The reaction that involves coupling of an aryl, benzyl or vinyl halide or triflate with stannane in presence of $\text{Pd}{\left({\text{PPh}}_{\text{3}}\right)}_{\text{4}}$.

(b)

Interpretation Introduction

Interpretation:

The compound 2 has to be synthesised.

Concept Introduction:

Suzuki reaction: It involves coupling of an aryl, a benzyl or vinyl halide with organoborane in presence of palladium catalyst which is indicated as follows,

  $\begin{array}{l}{\text{R}}_{\text{1}}{\text{-BY}}_{\text{2}}{\text{+R}}_{\text{2}}\text{-X}\underset{Base}{\overset{Pdcatalyst}{\to }}{\text{R}}_{\text{1}}{\text{-R}}_{\text{2}}\\ Here{\text{R}}_{\text{1}}{\text{-BY}}_{\text{2}}\Rightarrow Organoboron\\ {\text{R}}_{\text{2}}\text{-X}\Rightarrow Organohalide\\ {\text{R}}_{\text{1}}{\text{-R}}_{\text{2}}\Rightarrow resultingcoupledproduct\end{array}$

Stille coupling reaction: The reaction that involves coupling of an aryl, benzyl or vinyl halide or triflate with stannane in presence of $\text{Pd}{\left({\text{PPh}}_{\text{3}}\right)}_{\text{4}}$.