Chapter 23, Problem 55PP

Interpretation Introduction

Interpretation:

The structure for the product obtained when given compound is treated with excess $t\text{-BuLi}$, excess ${\text{ZnCl}}_{\text{2}}$, excess $\text{4-}$ iodotoluene, ${\text{Pd(PPh}}_{\text{3}}{\text{)}}_{\text{4}}$ should be identified.

Concept Introduction:

Preparation of organolithium: They are prepared by reaction of organohalide in presence of two equivalents of $Li$.

Preparation of organozinc: They are prepared by reaction of alkyl halide with zinc which results in insertion of zinc into $\text{C-halide}$ bond in the alkyl halide

Negishi reaction: It describes how the product obtained when organometallic compound containing $\text{Zn,}\text{Al}or\text{Zr}$ is coupled with organic electrophile in presence of palladium or nickel catalyst.