Calculate the average per-site, per-generation, nonsynonymous substitution rate between D. ananassae and the other three species. Also, give inputs about the type of selection of operating on the nonsynonymous sites based on the difference between the rate calculated in this part and question 1. Given: In the given study, a hypothetical gene encodes for the transcription factors in various species of Drosophila. According to the diagram given below, one exon of this gene is sequenced in four species. The matrix shows the number of synonymous and nonsynonymous substitutions between pairs of species of Drosophila, which evolved as a result of evolution. There are 2000 nonsynonymous and 600 synonymous substitutions sites of the exon. Introduction: The mutation rate is the rate used to calculate the frequency of new mutation in a single gene or one single organism, which have evolved over the time. The substitution rate is the rate which checks the DNA (deoxyribonucleic acid) sequence as the number of nucleotide substitute per site per unit of time.

Question

Want to see the full answer?

Answer 1

Question

Chapter 23, Problem 4Q

Summary Introduction

To review:

Calculate the average per-site, per-generation, nonsynonymous substitution rate between D. ananassae and the other three species. Also, give inputs about the type of selection of operating on the nonsynonymous sites based on the difference between the rate calculated in this part and question 1.

Given:

In the given study, a hypothetical gene encodes for the transcription factors in various species of Drosophila. According to the diagram given below, one exon of this gene is sequenced in four species.

The matrix shows the number of synonymous and nonsynonymous substitutions between pairs of species of Drosophila, which evolved as a result of evolution. There are 2000 nonsynonymous and 600 synonymous substitutions sites of the exon.

Introduction:

The mutation rate is the rate used to calculate the frequency of new mutation in a single gene or one single organism, which have evolved over the time. The substitution rate is the rate which checks the DNA (deoxyribonucleic acid) sequence as the number of nucleotide substitute per site per unit of time.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?

You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.

You implant an FGF10-coated bead into the anterior flank of a chicken embryo, directly below the level of the wing bud. What is the phenotype of the resulting ectopic limb? Briefly describe the expected expression domains of 1) Shh, 2) Tbx4, and 3) Tbx5 in the resulting ectopic limb bud.