(a) Interpretation: The reason for the requirement of ATP hydrolysis by the 26S proteasome should be determined. Concept introduction: Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

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Answer 1

Question

Chapter 23, Problem 4P

Interpretation Introduction

(a)

Interpretation:

The reason for the requirement of ATP hydrolysis by the 26S proteasome should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

Interpretation Introduction

(b)

Interpretation:

The reason for small peptides can be hydrolyzed deprived of the ATP use should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

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Answer 2

Question

Chapter 23, Problem 4P

Interpretation Introduction

(a)

Interpretation:

The reason for the requirement of ATP hydrolysis by the 26S proteasome should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

Interpretation Introduction

(b)

Interpretation:

The reason for small peptides can be hydrolyzed deprived of the ATP use should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

Expert Solution & Answer

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Answer 3

Question

Chapter 23, Problem 4P

Interpretation Introduction

(a)

Interpretation:

The reason for the requirement of ATP hydrolysis by the 26S proteasome should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

Interpretation Introduction

(b)

Interpretation:

The reason for small peptides can be hydrolyzed deprived of the ATP use should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

Expert Solution & Answer

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Answer 4

Question

Chapter 23, Problem 4P

Interpretation Introduction

(a)

Interpretation:

The reason for the requirement of ATP hydrolysis by the 26S proteasome should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

Interpretation Introduction

(b)

Interpretation:

The reason for small peptides can be hydrolyzed deprived of the ATP use should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

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Answer 5

Chapter 23, Problem 4P

Interpretation Introduction

(a)

Interpretation:

The reason for the requirement of ATP hydrolysis by the 26S proteasome should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

Interpretation Introduction

(b)

Interpretation:

The reason for small peptides can be hydrolyzed deprived of the ATP use should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

Answer 6

Chapter 23, Problem 4P

Interpretation Introduction

(a)

Interpretation:

The reason for the requirement of ATP hydrolysis by the 26S proteasome should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

Answer 7

Chapter 23, Problem 4P

Interpretation Introduction

(a)

Interpretation:

The reason for the requirement of ATP hydrolysis by the 26S proteasome should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

Answer 8

Interpretation Introduction

(b)

Interpretation:

The reason for small peptides can be hydrolyzed deprived of the ATP use should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

Answer 9

Interpretation Introduction

(b)

Interpretation:

The reason for small peptides can be hydrolyzed deprived of the ATP use should be determined.

Concept introduction:

Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.

Answer 10

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Answer 11

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Answer 12

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Answer 13

Ch. 23 - Prob. 1P Ch. 23 - Prob. 2P Ch. 23 - Prob. 3P Ch. 23 - Prob. 4P Ch. 23 - Prob. 5P Ch. 23 - Prob. 6P Ch. 23 - Prob. 7P Ch. 23 - Prob. 8P Ch. 23 - Prob. 9P Ch. 23 - Prob. 10P

Solution Summary: The author explains that the 26S proteasome is a 2.5-MDa molecular machine that catalyzes the degradation of the protein.

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Chapter 23 Solutions