Biochemistry
Biochemistry
8th Edition
ISBN: 9781464126109
Author: Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr., Lubert Stryer
Publisher: W. H. Freeman
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Chapter 23, Problem 25P
Interpretation Introduction

Interpretation:

The way by which Argininosuccinic aciduria can be treated should be determined.

Concept introduction:

The urea cycle is a series of biochemical reactions which involve the formation of urea (NH2)2CO from the ammonia (NH3). It is also known as the ornithine cycle. It helps in the excretion of toxic ammonia by converting into urea. This cycle takes place in ureotelic organisms. Argininosuccinase or argininosuccinate lyase or ASL is an enzyme which catalyzes the reversible breakdown of argininosuccinate and produces arginine and fumarate.

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