NESTER'S MICROBIOLOGY: A HUMAN PERSPECT
9th Edition
ISBN: 9781260161373
Author: Anderson, SALM
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 23, Problem 2CT
Summary Introduction
To review:
The colonization of wound by non-invasive bacteria causes disease.
Given:
Introduction:
Non-invasive bacteria are those bacteria which do not cause direct damage to the parts of the body. They affect by causing the release of toxins from bacteria resulting in disruption of the immune system responses of the body. The bacteria are classified as invasive and non-invasive bacteria and this classification has an important role in determining the treatment therapy for various diseases related to bacteria.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 23 Solutions
NESTER'S MICROBIOLOGY: A HUMAN PERSPECT
Ch. 23 - What property of Staphylococcus epidermidis helps...Ch. 23 - Prob. 2SACh. 23 -
3. Name two underlying conditions that predispose...Ch. 23 - Give two sources of Pseudomonas aeruginosa.Ch. 23 -
5. Outline the pathogenesis of tetanus.
Ch. 23 -
6. Explain why C. tetani can be cultivated from...Ch. 23 - Prob. 7SACh. 23 - Prob. 8SACh. 23 -
9. What is a synergistic infection? How might one...Ch. 23 - Why is sporotrichosis sometimes called rose...
Ch. 23 - Which of the following about Staphylococcus aureus...Ch. 23 - Prob. 2MCCh. 23 - Prob. 3MCCh. 23 - Prob. 4MCCh. 23 - Prob. 5MCCh. 23 - Prob. 6MCCh. 23 - Prob. 7MCCh. 23 - Prob. 8MCCh. 23 - Prob. 9MCCh. 23 - Prob. 10MCCh. 23 - Prob. 1ACh. 23 -
2. An army field nurse working at a mobile...Ch. 23 -
1. In what way would the incidence of tetanus at...Ch. 23 - Prob. 2CT
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