EBK CONCEPTS OF GENETICS
EBK CONCEPTS OF GENETICS
12th Edition
ISBN: 9780134818979
Author: Killian
Publisher: YUZU
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Chapter 23, Problem 22ESP

(a)

Summary Introduction

To describe: The gene which is likely to act earlier in the pathway responsible for the development of vulva.

Introduction: Vulva is an opening in the mid of the body of C. elegans. Eggs are laid through this opening, and this opening is formed during the developmental stages of the larva.

(b)

Summary Introduction

To determine: The phenotype that is expected to form from the double mutant.

Introduction: Initially, the gonadal anchor cell is determined, and then the second round of cell-cell interaction is initiated, which leads to the formation of the vulva. This interaction involves the cells which are present in gonads and the precursor cells.

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.
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