To review:
Whether the following statements are true or false:
a. The reactions of beta-oxidation crop fatty acids into three-carbon pyruvate units.
b. Most amino acids are converted into products that are oxidized by beta-oxidation.
c. The final common pathway for carbohydrate, protein, and lipid catabolism is the same.
d. Fat oxidation generates more ATP than protein or carbohydrate catabolism.
e. Fat and protein catabolism takes place primarily in the cytosol.
Introduction:
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Human Anatomy & Physiology (2nd Edition)
- For each of the following conditions, state whether this condition would be occurring during gluconeogenesis, glycolysis, or both in liver cells. a. Transporting malate from the cytosol into the mitochondria. _____________ b. Transporting pyruvate from the cytosol into the mitochondria. _____________ c. We would have an increased (or increasing) concentration of F26BP. __________ d. Increased concentration of F6P.__________ e. Hexokinase IV (or glucokinase) is found in the nucleus of the cell. __________ f. The enzyme that synthesizes/breaks down F26BP is phosphorylated. __________ g. Elevated levels of glucagon in the blood. ____________arrow_forwardGluconeogenesis occurs in liver and kidney. Which is of the following enzyme are important for gluconeogenesis are expressed exclusively in these tissues? Select one: a. Glucose-6-phosphatase b. Fructose-1,6-Bisphosphatase c. Phosphoenolpyruvate carboxykinase d. Pyruvate carboxylasearrow_forwardWhich of the following steps does NOT require ATP? O A. Conversion of glucose to glucose 6-phosphate O B. Conversion of malate to pyruvate O C. Conversion of pyruvate to oxaloacetate O D. Activation of hormone sensitive lipase by PKA O E. Inactivation of glycogen synthase by PKA is an intermediate metabolite linkage between carbohydrate and fat metabolism. O A. Malate O B. Oxaloacetate OC. Glucose 6-P O D. Acetyl COA O E. Malonyl COAarrow_forward
- Which of the following statements concerning gluconeogenesis is NOT true? a. Gluconeogenesis is to make glucose from glycogen. b. Many of the reactions of gluconeogenesis are glycolytic reactions going in reverse. c. The process of gluconeogenesis consumes ATP. d. The process of gluconeogenesis is regulated by ATP. e. Gluconeogenesis maintains the blood glucose level long after all dietary glucose has been absorbed and oxidized.arrow_forwardWhich of the following is the chemical end product of fatty-acids metabolized in the beta-oxidation pathway? Select one: a. Beta-carotine b. Free-radicals c. Lactic acid d. Acetyl-CoA e. Pyruvatearrow_forwardA major pathway for metabolism of ethanol is shown below. Humans consuming a large fraction of their calories in the form of ethanol may become hypoglycemic. This is because: Ethanol is a good solvent, and it dissolves the membranes of the mitochondria, where some of the gluconeogenic enzymes reside. b. Ethanol metabolism indirectly inhibits pyruvate kinase, by consuming NAD. d. Ethanol metabolism indirectly inhibits lactate dehydrogenase, by consuming NAD. f. The assertion in the question is incorrect, because acetyl-CoA can be used for synthesis of glucose. g. Ethanol metabolism indirectly inhibits pyruvate carboxylase, by consuming NAD. h. Ethanol metabolism indirectly inhibits phosphoenolpyruvate carboxykinase, by consuming NAD.arrow_forward
- Which of the following is true?a. Triglycerides have the least energy content per gram of the three majorenergy sources in the body.b. Fat catabolism generates new triglycerides for storage in adipose tissue.c. By mass, the total-body content of carbohydrates exceeds that of total triglycerides.d. Catabolism of fatty acids occurs in two-carbon steps.e. Triglycerides are the major lipids found in plasma membranesarrow_forwardIn the context of fatty acid oxidation to acetyl CoA, indicate whether each of the following substances is involved in (1) fatty acid activation, (2) fatty acid trans-port, or (3) b-oxidation pathway. More than one choice may be correct in a given situation. a. AMp b. FAD c. Acyl CoA d. H2Oarrow_forwardComplete the table below. Consider docosanoic acid (C21H43CO2H) Questions Solutions Answers a. Label the alpha and beta carbons. b. Draw the acetyl CoA derived from this fatty acid. c. How many acetyl CoA molecules are formed by complete B-oxidation? d. How many cycles of B-oxidation are needed for complete oxidation? e. How many molecules of ATP are formed from the complete catabolism of this fatty acid?arrow_forward
- Which of the following statements concerning the enzyme regulation is CORRECT? Select one: A. Citrate is the allosteric inhibitor of hexokinase. B. AMP is the alloseric activator of pyruvate dehydrogenase. C. Glucose-6-phosphate is the allosteric activator for phosphofructokinase. D. ATP is the activator of pyruvate kinase.arrow_forwardWhich of the following statements regarding glycogen are true? A. Glucose from glycogen can be metabolized anaerobically B. Approximately 1-2% of muscle weight is glycogen, whereas 10-15% of liver weight is glycogen C. It is faster for the muscle to obtain energy from glycogen than from lipids D. A and B are true E. B and C are true F. Both A, B, and C are truearrow_forwardWhich of the following statements is/are TRUE about fatty acid activation before β-oxidation? I. The process consumes energy equivalent to two moles of ATP. II. The fatty acid is activated by ATP to give a fatty acyl-CoA.arrow_forward
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