The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat. Concept Introduction : The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes . Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene. To find: The major product of cyclohexyl amine in Hofmann elimination Draw and analyze the structure of cyclohexyl amine

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Answer 1

Question

Chapter 22.9, Problem 23PTS

(a)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of cyclohexyl amine in Hofmann elimination

Draw and analyze the structure of cyclohexyl amine

(b)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of (R)-3-methyl-2-butanamine in Hofmann elimination

Draw and analyze the structure of (R)-3-methyl-2-butanamine

(c)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of N,N-dimethyl-1-phenylpropan-2-amine in Hofmann elimination

Draw and analyze the structure of N,N-dimethyl-1-phenylpropan-2-amine.

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Answer 2

Question

Chapter 22.9, Problem 23PTS

(a)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of cyclohexyl amine in Hofmann elimination

Draw and analyze the structure of cyclohexyl amine

(b)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of (R)-3-methyl-2-butanamine in Hofmann elimination

Draw and analyze the structure of (R)-3-methyl-2-butanamine

(c)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of N,N-dimethyl-1-phenylpropan-2-amine in Hofmann elimination

Draw and analyze the structure of N,N-dimethyl-1-phenylpropan-2-amine.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 22.9, Problem 23PTS

(a)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of cyclohexyl amine in Hofmann elimination

Draw and analyze the structure of cyclohexyl amine

(b)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of (R)-3-methyl-2-butanamine in Hofmann elimination

Draw and analyze the structure of (R)-3-methyl-2-butanamine

(c)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of N,N-dimethyl-1-phenylpropan-2-amine in Hofmann elimination

Draw and analyze the structure of N,N-dimethyl-1-phenylpropan-2-amine.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 22.9, Problem 23PTS

(a)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of cyclohexyl amine in Hofmann elimination

Draw and analyze the structure of cyclohexyl amine

(b)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of (R)-3-methyl-2-butanamine in Hofmann elimination

Draw and analyze the structure of (R)-3-methyl-2-butanamine

(c)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of N,N-dimethyl-1-phenylpropan-2-amine in Hofmann elimination

Draw and analyze the structure of N,N-dimethyl-1-phenylpropan-2-amine.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 5

Chapter 22.9, Problem 23PTS

(a)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of cyclohexyl amine in Hofmann elimination

Draw and analyze the structure of cyclohexyl amine

(b)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of (R)-3-methyl-2-butanamine in Hofmann elimination

Draw and analyze the structure of (R)-3-methyl-2-butanamine

(c)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of N,N-dimethyl-1-phenylpropan-2-amine in Hofmann elimination

Draw and analyze the structure of N,N-dimethyl-1-phenylpropan-2-amine.

Answer 6

Chapter 22.9, Problem 23PTS

(a)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of cyclohexyl amine in Hofmann elimination

Draw and analyze the structure of cyclohexyl amine

Answer 7

Chapter 22.9, Problem 23PTS

(a)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of cyclohexyl amine in Hofmann elimination

Draw and analyze the structure of cyclohexyl amine

Answer 8

(b)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of (R)-3-methyl-2-butanamine in Hofmann elimination

Draw and analyze the structure of (R)-3-methyl-2-butanamine

Answer 9

(b)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of (R)-3-methyl-2-butanamine in Hofmann elimination

Draw and analyze the structure of (R)-3-methyl-2-butanamine

Answer 10

(c)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of N,N-dimethyl-1-phenylpropan-2-amine in Hofmann elimination

Draw and analyze the structure of N,N-dimethyl-1-phenylpropan-2-amine.

Answer 11

(c)

Interpretation Introduction

Interpretation: The major products are to be found when the given compounds are treated with excess methyl iodide followed by aqueous silver oxide and heat.

Concept Introduction:

The reagents such as methyl iodide and silver oxide are used as the reaction conditions which are called Hofmann elimination. The amines undergo exhaustive alkylation in the presence of excess methyl iodide producing quaternaryammonium salt which is excellent leaving group. After treatment with strong base, aqueous silver oxide and heat, the quaternary ammonium salt provides alkenes. Alkene formation involves in E2 elimination. Through E2 elimination, the major product is less substituted alkene with trace amount of more substituted alkene.

To find: The major product of N,N-dimethyl-1-phenylpropan-2-amine in Hofmann elimination

Draw and analyze the structure of N,N-dimethyl-1-phenylpropan-2-amine.

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 22.2 - Prob. 1LTS Ch. 22.2 - Prob. 1PTS Ch. 22.2 - Prob. 2PTS Ch. 22.2 - Prob. 3ATS Ch. 22.3 - Prob. 4CC Ch. 22.3 - Prob. 5CC Ch. 22.3 - Prob. 6CC Ch. 22.3 - Prob. 7CC Ch. 22.3 - Prob. 8CC Ch. 22.3 - Prob. 9CC

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Chapter 22 Solutions