ORGANIC CHEMISTRY W/OWL
ORGANIC CHEMISTRY W/OWL
9th Edition
ISBN: 9781305717527
Author: McMurry
Publisher: CENGAGE C
Question
Book Icon
Chapter 22.7, Problem 16P
Interpretation Introduction

a)

ORGANIC CHEMISTRY W/OWL, Chapter 22.7, Problem 16P , additional homework tip  1

Interpretation:

Using an alkylation reaction as the key step how the compound shown can be prepared is to be given.

Concept introduction:

An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product, the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).

To give:

Using an alkylation reaction as the key step how to prepare the compound shown.

Interpretation Introduction

b)

ORGANIC CHEMISTRY W/OWL, Chapter 22.7, Problem 16P , additional homework tip  2

Interpretation:

Using an alkylation reaction as the key step how the compound shown can be prepared.

Concept introduction:

An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).

To give:

Using an alkylation reaction as the key step how to prepare the compound shown.

Interpretation Introduction

c)

ORGANIC CHEMISTRY W/OWL, Chapter 22.7, Problem 16P , additional homework tip  3

Interpretation:

Using an alkylation reaction as the key step how the compound shown can be prepared.

Concept introduction:

An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by aSN2reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).

To give:

Using an alkylation reaction as the key step how to prepare the compound shown.

Interpretation Introduction

d)

ORGANIC CHEMISTRY W/OWL, Chapter 22.7, Problem 16P , additional homework tip  4

Interpretation:

Using an alkylation reaction as the key step how the compound shown can be prepared.

Concept introduction:

An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).

To give:

Using an alkylation reaction as the key step how to prepare the compound shown.

Interpretation Introduction

e)

ORGANIC CHEMISTRY W/OWL, Chapter 22.7, Problem 16P , additional homework tip  5

Interpretation:

Using an alkylation reaction as the key step how the compound shown can be prepared.

Concept introduction:

An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).

To give:

Using an alkylation reaction as the key step how to prepare the compound shown.

Interpretation Introduction

f)

ORGANIC CHEMISTRY W/OWL, Chapter 22.7, Problem 16P , additional homework tip  6

Interpretation:

Using an alkylation reaction as the key step how the compound shown can be prepared.

Concept introduction:

An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).

To give:

Using an alkylation reaction as the key step how to prepare the compound shown.

Blurred answer
Students have asked these similar questions
A cylinder contains 12 L of water vapour at 150˚C and 5 atm. The temperature of the water vapour is raised to 175˚C, and the volume of the cylinder is reduced to 8.5 L. What is the final pressure of the gas in atmospheres? assume that the gas is ideal
On the next page is an LC separation of the parabens found in baby wash. Parabens are suspected in a link to breast cancer therefore an accurate way to quantitate them is desired. a. In the chromatogram, estimate k' for ethyl paraben. Clearly indicate what values you used for all the terms in your calculation. b. Is this a "good" value for a capacity factor? Explain. c. What is the resolution between n-Propyl paraben and n-Butyl paraben? Again, indicate clearly what values you used in your calculation. MAU | Methyl paraben 40 20 0 -2 Ethyl paraben n-Propyl paraben n-Butyl paraben App ID 22925 6 8 min
d. In Figure 4, each stationary phase shows some negative correlation between plate count and retention factor. In other words, as k' increases, N decreases. Explain this relationship between k' and N. Plate Count (N) 4000 3500 2500 2000 1500 1000 Figure 4. Column efficiency (N) vs retention factor (k') for 22 nonionizable solutes on FMS (red), PGC (black), and COZ (green). 3000 Eluent compositions (acetonitrile/water, A/W) were adjusted to obtain k' less than 15, which was achieved for most solutes as follows: FMS (30/70 A/W), PGC (60/40), COZ (80/20). Slightly different compositions were used for the most highly retained solutes. All columns were 50 mm × 4.6 mm id and packed with 5 um particles, except for COZ, which was packed with 3 um particles. All other chromatographic conditions were constant: column length 5 cm, column j.§. 4.6 mm, flow rate 2 mL/min, column temperature 40 °C, and injection volume 0.5 μL Log(k'x/K'ethylbenzene) FMS 1.5 1.0 0.5 0.0 ཐྭ ཋ ཤྩ བྷྲ ; 500 0 5 10…

Chapter 22 Solutions

ORGANIC CHEMISTRY W/OWL

Ch. 22.7 - Draw a resonance structure of the acetonitrile...Ch. 22.7 - Why do you suppose ketone halogenations in acidic...Ch. 22.7 - Prob. 13PCh. 22.7 - Prob. 14PCh. 22.7 - Prob. 15PCh. 22.7 - Prob. 16PCh. 22.SE - Prob. 17VCCh. 22.SE - Prob. 18VCCh. 22.SE - Prob. 19VCCh. 22.SE - Prob. 20MPCh. 22.SE - Predict the product(s) and provide the mechanism...Ch. 22.SE - Predict the product(s) and provide the mechanism...Ch. 22.SE - Prob. 23MPCh. 22.SE - In the Hell–Volhard–Zelinskii reaction, only a...Ch. 22.SE - Prob. 25MPCh. 22.SE - Nonconjugated , -unsaturated ketones, such as...Ch. 22.SE - Prob. 27MPCh. 22.SE - Using curved arrows, propose a mechanism for the...Ch. 22.SE - Prob. 29MPCh. 22.SE - One of the later steps in glucose biosynthesis is...Ch. 22.SE - The Favorskii reaction involves treatment of an...Ch. 22.SE - Treatment of a cyclic ketone with diazomethane is...Ch. 22.SE - Prob. 33MPCh. 22.SE - Amino acids can be prepared by reaction of alkyl...Ch. 22.SE - Amino acids can also be prepared by a two-step...Ch. 22.SE - Heating carvone with aqueous sulfuric acid...Ch. 22.SE - Identify all the acidic hydrogens (pKa 25) in the...Ch. 22.SE - Rank the following compounds in order of...Ch. 22.SE - Prob. 39APCh. 22.SE - Base treatment of the following , -unsaturated...Ch. 22.SE - Prob. 41APCh. 22.SE - Prob. 42APCh. 22.SE - Prob. 43APCh. 22.SE - Which, if any, of the following compounds can be...Ch. 22.SE - Prob. 45APCh. 22.SE - Prob. 46APCh. 22.SE - Prob. 47APCh. 22.SE - How might you convert geraniol into either ethyl...Ch. 22.SE - Prob. 49APCh. 22.SE - One way to determine the number of acidic...Ch. 22.SE - Prob. 51APCh. 22.SE - Prob. 52APCh. 22.SE - Prob. 53APCh. 22.SE - Prob. 54APCh. 22.SE - Prob. 55APCh. 22.SE - Prob. 56APCh. 22.SE - All attempts to isolate primary and secondary...Ch. 22.SE - How would you synthesize the following compounds...Ch. 22.SE - Prob. 59APCh. 22.SE - Prob. 60APCh. 22.SE - Prob. 61APCh. 22.SE - Prob. 62APCh. 22.SE - As far back as the 16th century, South American...Ch. 22.SE - The key step in a reported laboratory synthesis of...Ch. 22.SE - Prob. 65AP
Knowledge Booster
Background pattern image
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Chemistry
Chemistry
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Cengage Learning
Text book image
Chemistry
Chemistry
ISBN:9781259911156
Author:Raymond Chang Dr., Jason Overby Professor
Publisher:McGraw-Hill Education
Text book image
Principles of Instrumental Analysis
Chemistry
ISBN:9781305577213
Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:Cengage Learning
Text book image
Organic Chemistry
Chemistry
ISBN:9780078021558
Author:Janice Gorzynski Smith Dr.
Publisher:McGraw-Hill Education
Text book image
Chemistry: Principles and Reactions
Chemistry
ISBN:9781305079373
Author:William L. Masterton, Cecile N. Hurley
Publisher:Cengage Learning
Text book image
Elementary Principles of Chemical Processes, Bind...
Chemistry
ISBN:9781118431221
Author:Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:WILEY