Anatomy & Physiology: An Integrative Approach
4th Edition
ISBN: 9781264265435
Author: Michael McKinley
Publisher: Mcgraw-hill Higher Education (us)
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Question
Chapter 22.5, Problem 20WDYL
Summary Introduction
To determine:
The way in which central tolerance differ from peripheral tolerance.
Concept introduction:
The process of deletion of T lymphocytes in the thymus that is self-reactive is known as central tolerance. The peripheral tolerance is mediated by the regulatory T cells that suppress CD+ T cells. The apoptosis and negative selection occur in primary lymphoid organs.
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Students have asked these similar questions
19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 22 Solutions
Anatomy & Physiology: An Integrative Approach
Ch. 22.1 - Which pathogen must enter a cell to replicate?...Ch. 22.2 - Prob. 2WDYLCh. 22.2 - What is the definition of a cytokine? How are...Ch. 22.2 - Prob. 4WDYLCh. 22.3 - Prob. 5WDYLCh. 22.3 - Prob. 6WDYLCh. 22.3 - Prob. 7WDYLCh. 22.3 - How do NK cells accomplish the task of eliminating...Ch. 22.3 - Prob. 9WDYLCh. 22.3 - Prob. 10WDYL
Ch. 22.3 - Prob. 11WDYLCh. 22.3 - Prob. 12WDYLCh. 22.4 - Prob. 13WDYLCh. 22.4 - What distinguishes a hapten from an antigen?Ch. 22.4 - Prob. 15WDYLCh. 22.4 - Which type of MHC class molecules is found on all...Ch. 22.4 - Prob. 17WDYLCh. 22.5 - Prob. 18WDYLCh. 22.5 - What would happen if a thymocyte that failed the...Ch. 22.5 - Prob. 20WDYLCh. 22.6 - Prob. 21WDYLCh. 22.6 - How do cytokines released by helper T-lymphocytes...Ch. 22.6 - Prob. 23WDYLCh. 22.6 - Prob. 24WDYLCh. 22.6 - Prob. 25WDYLCh. 22.7 - Prob. 26WDYLCh. 22.7 - Prob. 27WDYLCh. 22.7 - Prob. 28WDYLCh. 22.8 - Prob. 29WDYLCh. 22.8 - What are the six major functions of antibodies?...Ch. 22.8 - Which subclass of antibodies is most prevalent?...Ch. 22.9 - Prob. 32WDYLCh. 22.9 - Prob. 33WDYLCh. 22.9 - Prob. 34WDYLCh. 22 - _____ 1. All of the following are phagocytic cells...Ch. 22 - _____ 2. This cell releases cytokines to activate...Ch. 22 - _____ 3. This cell is activated by binding...Ch. 22 - _____ 4. These two cells destroy an infected cell...Ch. 22 - _____ 5. All of the following are functions of...Ch. 22 - _____ 6. The four characteristics of adaptive...Ch. 22 - _____ 7. During which process does additional...Ch. 22 - _____ 8. This chemical is released by...Ch. 22 - _____ 9. The correct sequence of the major events...Ch. 22 - Prob. 10DYKBCh. 22 - Compare the general characteristics of innate...Ch. 22 - Define the inflammatory response, and explain its...Ch. 22 - Describe an antigen.Ch. 22 - Describe class I and class II MHC molecules, and...Ch. 22 - Prob. 15DYKBCh. 22 - Prob. 16DYKBCh. 22 - Explain the general function of cytotoxic...Ch. 22 - Describe both the function of antibodies and...Ch. 22 - There are two branches of adaptive immunity:...Ch. 22 - Prob. 20DYKBCh. 22 - Prob. 1CALCh. 22 - Prob. 2CALCh. 22 - Prob. 3CALCh. 22 - Prob. 4CALCh. 22 - Prob. 5CALCh. 22 - Prob. 1CSLCh. 22 - Prob. 2CSLCh. 22 - Prob. 3CSL
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