Videos
(a)
Interpretation:
The method of synthesis of given ester has to be stated with the help of crossed Claisen condensation.
Concept introduction:
In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.
(b)
Interpretation:
The method of synthesis of given ester is to be stated with the help of crossed Claisen condensation.
Concept introduction:
In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.
(c)
Interpretation:
The method of synthesis of given ester is to be stated with the help of crossed Claisen condensation.
Concept introduction:
In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.
(d)
Interpretation:
The method of synthesis of given ester is to be stated with the help of crossed Claisen condensation.
Concept introduction:
In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.
Want to see the full answer?
Check out a sample textbook solution
Chapter 22 Solutions
Organic Chemistry Plus Mastering Chemistry with Pearson eText -- Access Card Package (9th Edition) (New in Organic Chemistry)
- Provide the semi-developed formula of isooxazole obtained by reacting acetylacetone and hydroxylamine.arrow_forwardGiven a 1,3-dicarbonyl compound (R1-CO-CH2-CO-R2), indicate the formula of the compound obtaineda) if I add hydroxylamine (NH2OH) to give an isooxazole.b) if I add thiosemicarbazide (NH2-CO-NH-NH2) to give an isothiazole.arrow_forwardAn orange laser has a wavelength of 610 nm. What is the energy of this light?arrow_forward
- The molar absorptivity of a protein in water at 280 nm can be estimated within ~5-10% from its content of the amino acids tyrosine and tryptophan and from the number of disulfide linkages (R-S-S-R) between cysteine residues: Ε280 nm (M-1 cm-1) ≈ 5500 nTrp + 1490 nTyr + 125 nS-S where nTrp is the number of tryptophans, nTyr is the number of tyrosines, and nS-S is the number of disulfide linkages. The protein human serum transferrin has 678 amino acids including 8 tryptophans, 26 tyrosines, and 19 disulfide linkages. The molecular mass of the most dominant for is 79550. Predict the molar absorptivity of transferrin. Predict the absorbance of a solution that’s 1.000 g/L transferrin in a 1.000-cm-pathlength cuvet. Estimate the g/L of a transferrin solution with an absorbance of 1.50 at 280 nm.arrow_forwardIn GC, what order will the following molecules elute from the column? CH3OCH3, CH3CH2OH, C3H8, C4H10arrow_forwardBeer’s Law is A = εbc, where A is absorbance, ε is the molar absorptivity (which is specific to the compound and wavelength in the measurement), and c is concentration. The absorbance of a 2.31 × 10-5 M solution of a compound is 0.822 at a wavelength of 266 nm in a 1.00-cm cell. Calculate the molar absorptivity at 266 nm.arrow_forward
- How to calculate % of unknown solution using line of best fit y=0.1227x + 0.0292 (y=2.244)arrow_forwardGiven a 1,3-dicarbonyl compound, state the (condensed) formula of the compound obtaineda) if I add hydroxylamine (NH2OH) to give an isooxazole.b) if I add thiosemicarbazide (NH2-CO-NH-NH2) to give an isothiazole.arrow_forwardComplete the following acid-base reactions and predict the direction of equilibrium for each. Justify your prediction by citing pK values for the acid and conjugate acid in each equilibrium. (a) (b) NHs (c) O₂N NH NH OH H₁PO₁arrow_forward
- 23.34 Show how to convert each starting material into isobutylamine in good yield. ཅ ནད ཀྱི (b) Br OEt (c) (d) (e) (f) Harrow_forwardPlease help me Please use https://app.molview.com/ to draw this. I tried, but I couldn't figure out how to do it.arrow_forwardPropose a synthesis of 1-butanamine from the following: (a) a chloroalkane of three carbons (b) a chloroalkane of four carbonsarrow_forward
EBK A SMALL SCALE APPROACH TO ORGANIC LChemistryISBN:9781305446021Author:LampmanPublisher:CENGAGE LEARNING - CONSIGNMENT
Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning