The method of preparation of given compound using malonic ester synthesis is to be stated. Concept introduction: Deprotonation of malonic ester gives enolate ion. This enolate ion is alkylated by an unhindered alkyl halide , tosylates or any other electrophilic species through S N 2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

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Answer 1

Question

Chapter 22, Problem 22.72SP

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester gives enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

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Answer 2

Question

Chapter 22, Problem 22.72SP

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester gives enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

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Answer 3

Question

Chapter 22, Problem 22.72SP

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester gives enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

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Answer 4

Question

Chapter 22, Problem 22.72SP

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester gives enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

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Answer 5

Chapter 22, Problem 22.72SP

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester gives enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 6

Chapter 22, Problem 22.72SP

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester gives enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 7

Chapter 22, Problem 22.72SP

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester gives enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 8

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 9

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 10

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 11

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 22.2A - Prob. 22.2P Ch. 22.4 - Without looking back, propose a mechanism for the...Ch. 22.4 - Prob. 22.8P Ch. 22.4 - Prob. 22.9P Ch. 22.5A - Prob. 22.10P Ch. 22.5A - Prob. 22.11P Ch. 22.5B - Prob. 22.12P Ch. 22.5B - Predict the products of the following reactions....Ch. 22.5B - Which compounds will give positive iodoform tests?...Ch. 22.5C - Propose a mechanism for the acid-catalyzed...

Solution Summary: The author explains the method of preparation of given compound using malonic ester synthesis.

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Chapter 22 Solutions