The major product of the given crossed Claisen condensation has to be stated. Concept introduction: In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Question

Want to see the full answer?

Answer 1

Question

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Which of the following is true for a particular reaction if ∆G° is -40.0 kJ/mol at 290 K and –20.0 kJ/mol at 390 K?

What is the major product of the following reaction? O O OH OH 1. BH 2. H₂O₂, NaOH OH OH

Draw the products formed when each ester is hydrolyzed with water and sulfuric acid.

Answer 2

Question

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 6

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 7

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 8

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 9

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 10

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 11

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 12

Expert Solution & Answer

Answer 13

Expert Solution & Answer

Answer 14

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 15

Ch. 22.2A - Prob. 22.2P Ch. 22.4 - Without looking back, propose a mechanism for the...Ch. 22.4 - Prob. 22.8P Ch. 22.4 - Prob. 22.9P Ch. 22.5A - Prob. 22.10P Ch. 22.5A - Prob. 22.11P Ch. 22.5B - Prob. 22.12P Ch. 22.5B - Predict the products of the following reactions....Ch. 22.5B - Which compounds will give positive iodoform tests?...Ch. 22.5C - Propose a mechanism for the acid-catalyzed...

Solution Summary: The author explains that the major product of the given crossed Claisen condensation is shown below.

Concept explainers

Videos

Want to see the full answer?

Chapter 22 Solutions