(a)
Interpretation: Major products for the given set of reactions have to be found.
Concept Introduction:
The nitro group present in the compound is reduced to amino group by using Fe, Zn, Sn or SnCl2 in the presence of aqueous acid followed by the treatment with base such as NaOH. This reaction is more mild approach. It can be carried out in the presence of the other
To find: Using a reduction followed by base treatment, prepare the major product of (a)
Find the reaction of the starting material of (a) with Fe, H3O+
(b)
Interpretation: Major products for the given set of reactions have to be found.
Concept Introduction:
Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions.
Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.
Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.
To find: Using a reductive amination, prepare the major product of (b)
Decide the reaction and the nature of the product
(c)
Interpretation: Major products for the given set of reactions have to be found.
Concept introduction:
The reduction of lithium aluminum hydride on nitriles followed by water work-up gives amine with an additional carbon atom in their chain. This type of reaction is applied to increase the carbon skeleton and change in the identity of the functional group.
To find: The major product of the reaction (c)
Give for the formation of lithium salt by reduction
(d)
Interpretation: Major products for the given set of reactions have to be found.
Concept introduction:
The reduction of lithium aluminum hydride on nitriles followed by water work-up gives amine with an additional carbon atom in their chain. This type of reaction is applied to increase the carbon skeleton and change in the identity of the functional group.
To find: The major product of the reaction (d)
Give for the formation of lithium ion by reduction
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Chapter 22 Solutions
ORGANIC CHEMISTRY,SOLNS...-ETEXT+BOX
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- Give the product of the bimolecular elimination from each of the isomeric halogenated compounds. Reaction A Reaction B. КОВ CH₂ HotBu +B+ ко HOIBU +Br+ Templates More QQQ Select Cv Templates More Cras QQQ One of these compounds undergoes elimination 50x faster than the other. Which one and why? Reaction A because the conformation needed for elimination places the phenyl groups and to each other Reaction A because the conformation needed for elimination places the phenyl groups gauche to each other. ◇ Reaction B because the conformation needed for elimination places the phenyl groups gach to each other. Reaction B because the conformation needed for elimination places the phenyl groups anti to each other.arrow_forwardFive isomeric alkenes. A through each undergo catalytic hydrogenation to give 2-methylpentane The IR spectra of these five alkenes have the key absorptions (in cm Compound Compound A –912. (§), 994 (5), 1643 (%), 3077 (1) Compound B 833 (3), 1667 (W), 3050 (weak shoulder on C-Habsorption) Compound C Compound D) –714 (5), 1665 (w), 3010 (m) 885 (3), 1650 (m), 3086 (m) 967 (5), no aharption 1600 to 1700, 3040 (m) Compound K Match each compound to the data presented. Compound A Compound B Compound C Compound D Compoundarrow_forward7. The three sets of replicate results below were accumulated for the analysis of the same sample. Pool these data to obtain the most efficient estimate of the mean analyte content and the standard deviation. Lead content/ppm: Set 1 Set 2 Set 3 1. 9.76 9.87 9.85 2. 9.42 9.64 9.91 3. 9.53 9.71 9.42 9.81 9.49arrow_forward
- Draw the Zaitsev product famed when 2,3-dimethylpentan-3-of undergoes an El dehydration. CH₂ E1 OH H₁PO₁ Select Draw Templates More QQQ +H₂Oarrow_forwardComplete the clean-pushing mechanism for the given ether synthesia from propanol in concentrated sulfurica140°C by adding any mining aloms, bands, charges, nonbonding electron pairs, and curved arrows. Draw hydrogen bonded to cayan, when applicable. ore 11,0 HPC Step 1: Draw curved arrows Step 2: Complete the intend carved Q2Q 56 QQQ Step 3: Complete the intermediate and add curved Step 4: Modify the structures to draw the QQQ QQQarrow_forward6. In an experiment the following replicate set of volume measurements (cm3) was recorded: (25.35, 25.80, 25.28, 25.50, 25.45, 25.43) A. Calculate the mean of the raw data. B. Using the rejection quotient (Q-test) reject any questionable results. C. Recalculate the mean and compare it with the value obtained in 2(a).arrow_forward
- A student proposes the transformation below in one step of an organic synthesis. There may be one or more reactants missing from the left-hand side, but there are no products missing from the right-hand side. There may also be catalysts, small inorganic reagents, and other important reaction conditions missing from the arrow. • Is the student's transformation possible? If not, check the box under the drawing area. • If the student's transformation is possible, then complete the reaction by adding any missing reactants to the left-hand side, and adding required catalysts, inorganic reagents, or other important reaction conditions above and below the arrow. • You do not need to balance the reaction, but be sure every important organic reactant or product is shown. + T G OH де OH This transformation can't be done in one step.arrow_forwardMacmillan Leaming Draw the major organic product of the reaction. 1. CH3CH2MgBr 2. H+ - G Select Draw Templates More H о QQarrow_forwardDraw the condensed structure of 3-hydroxy-2-butanone. Click anywhere to draw the first atom of your structure.arrow_forward
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