Genetics: From Genes to Genomes
Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 22, Problem 27P

Through GWAS explorations, scientists have identified several SNPs linked to obesity in people who live in the United States. One of these SNPs was within a gene called FTO. Interestingly, a common FTO variant is associated with obesity, but only in people born after 1945. Moreover, the later the birth year, the higher the risk for obesity associated with this variant of FTO. Why would a genetic risk factor for obesity vary by birth year?

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Genetics: From Genes to Genomes

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