(a)
Interpretation: The synthesis of given analgesic compound from phenol and any other organic or inorganic reagents is to be stated.
Concept introduction: The replacement or substitution of one
(b)
Interpretation: The synthesis of given analgesic compound from phenol and any other organic or inorganic reagents is to be stated.
Concept introduction: The replacement or substitution of one functional group with another different functional group in any chemical reaction is termed as substitution reaction. The electron rich chemical species that contains negative charge or lone pair of electrons are known as nucleophile. In nucleophilc acyl substitution reaction, nucleophile takes the position of leaving group.
(c)
Interpretation: The synthesis of given analgesic compound from phenol and any other organic or inorganic reagents is to be stated.
Concept introduction: The replacement or substitution of one functional group with another different functional group in any chemical reaction is termed as substitution reaction. The electron rich chemical species that contains negative charge or lone pair of electrons are known as nucleophile. In nucleophilc acyl substitution reaction, nucleophile takes the position of leaving group.
Want to see the full answer?
Check out a sample textbook solutionChapter 22 Solutions
ORGANIC CHEMISTRY
- How would you convert benzoic acid (C6H5CO2H) to each compound?arrow_forwardWhat amide(s) can be used to prepare each amine by reduction?arrow_forwardIn the 1880's, Acetanilide, sold under the name Antifebrin, was widely used as a pain reliever and fever reducer. However, it had many adverse side effects, including cyanosis as a result of methemoglobinemia. The toxic side effects were the result of a small portion of acetanilide being hydrolyzed to aniline. Acetanilide was discontinued and replaced with phenacetin. Later studies show that both acetanilide and phenacetin are metabolized to acetaminophen. This metabolite, which we know as Tylenol, is responsible for the analgesic and antipyretic properties. Part 1: Show a detailed arrow pushing mechanism of the acid catalyzed hydrolysis of acetanilide to aniline Part 2: Propose a synthesis of Acetaminophen from phenol NH NH NH Phenacetin inophen Acetanilide Attach File Browse Local Files Browse Content Collectionarrow_forward
- Two reactions occur when sodium hydroxide is added to methyl salicylate. One is immediate and one only occurs with reflux over time. What type of reaction occurs immediately and with which functional group on methyl salicylate does it react? What type of reaction occurs with reflux over time and with which functional group on methyl salicylate does it react?arrow_forwardDraw the structure (including stereochemistry) of the cyclic hemiacetal(s) formed when each hydroxy carbonyl compound is treated with aqueous acid.arrow_forwardWhen trichloroacetaldehyde is dissolved in water, almost all of it is converted to the hydrate. Chloral hydrate, the product of the reaction, is a sedative that can be lethal. A cocktail laced with it is known—in detective novels,at least—as a “Mickey Finn.” Explain why an aqueous solution of trichloroacetaldehyde is almost all hydrate.arrow_forward
- Draw the product formed when CH3CH2CH2CH2NH2 reacts with each carbonyl compound in the presence of mild acidarrow_forwardWhat unsaturated carbonyl compound is formed by dehydration of each β-hydroxy carbonyl compound?arrow_forwardShow how to convert 4-methoxybenzyl chloride to each amine.arrow_forward
- What nitro compound, nitrile, and amide are reduced to each compound?arrow_forwardDraw the products formed when each acetal is treated with aqueous acid.arrow_forwardDraw the product formed when phenylacetic acid (C6H5CH2COOH) is treated with each reagent. With some reagents, no reaction occurs. (A - F)arrow_forward
- Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage LearningChemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage LearningOrganic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning