The preparation of haloperidol compound has to be proposed. Concept Introduction: Retrosynthetic analysis: In an organic synthesis , the transformation of target molecule into simpler precursor molecules regardless of any reactivity or interaction with reagents. A retrosynthetic analysis is involving the breaking of a bond to form two or more synthons.

Question

81. a. Propose a mechanism for the following reaction: OH CH2=CHCHC=N b. What is the product of the following reaction? HO H₂O N=CCH2CH2CH OH HO CH3CCH=CH2 H₂O C=N 82. Unlike a phosphonium ylide that reacts with an aldehyde or a ketone to form an alkene a sulfonium ulia

Answer 1

Question

Chapter 22, Problem 22.61P

(a)

Interpretation Introduction

Interpretation:

The preparation of haloperidol compound has to be proposed.

Concept Introduction:

Retrosynthetic analysis:

In an organic synthesis, the transformation of target molecule into simpler precursor molecules regardless of any reactivity or interaction with reagents. A retrosynthetic analysis is involving the breaking of a bond to form two or more synthons.

(b)

Interpretation Introduction

Interpretation:

The chirality of haloperidol, and the possible of number of isomers in the given synthesis has to be given.

Concept Introduction:

Stereoisomers and chiral:

Isomers differing only in their spatial arrangement of atoms are called as stereoisomers.

The geometric property of a molecule that cannot be superimposed on its mirror image is known as chirality. Chiral carbon is the one which is attached with four different groups or atoms.

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