Chapter 22, Problem 22.54P

Interpretation Introduction

(a)

Interpretation:

The formation of given compound using conjugate addition reaction is to be stated.

Concept Introduction:

The $\alpha ,\beta$-unsaturated esters or ketones give specifically conjugate addition on reaction with the Lithium dialkylcuprate compounds. The conjugate addition reaction is promoted by the presence of copper in the reagent.

Interpretation Introduction

(b)

Interpretation:

The formation of given compound using conjugate addition reaction is to be stated.

Concept Introduction:

The $\alpha ,\beta$-unsaturated esters or ketones give specifically conjugate addition on reaction with the Lithium dialkylcuprate compounds. The conjugate addition reaction is promoted by the presence of copper in the reagent.

Interpretation Introduction

(c)

Interpretation:

The formation of given compound using conjugate addition reaction is to be stated.

Concept Introduction:

The $\alpha ,\beta$-unsaturated esters or ketones give conjugate addition on reaction with diethyl malonate using $\text{NaOEt}$ as base. $\text{O}\text{Et}$ abstracts the acidic hydrogen of diethyl malonate . Then conjugate base of will attack at the double bond to form diethyl malonate derivative, which upon hydrolysis gives oxocarboxylic acid.

Interpretation Introduction

(d)

Interpretation:

The formation of given compound using conjugate addition reaction is to be stated.

Concept Introduction:

The $\alpha ,\beta$-unsaturated esters or ketones reacts with sodium cyanide in methanol solvent to form nitrile derivative of compound, which upon hydrolysis gives conjugated addition product.