Microbiology: An Introduction, Books a la Carte Plus Mastering Microbiology with Pearson eText -- Access Card Package (13th Edition)
13th Edition
ISBN: 9780134729336
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case, Derek Weber, Warner Bair
Publisher: PEARSON
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Chapter 22, Problem 1MCQ
Summary Introduction
Introduction:
Tetanus is an infectious disease of the nervous system caused by the bacteria, Clostridium tetani that initially causes stiffness of the muscles of the jaw and neck which later progresses to spasm of the entire body muscles. Fever, dysphagia, hypertension and tachycardia are the other symptoms of tetanus.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 22 Solutions
Microbiology: An Introduction, Books a la Carte Plus Mastering Microbiology with Pearson eText -- Access Card Package (13th Edition)
Ch. 22 - If Clostridium tetani is relatively sensitive to...Ch. 22 - Prob. 2RCh. 22 - Prob. 3RCh. 22 - Prob. 4RCh. 22 - Prob. 5RCh. 22 - Prob. 6RCh. 22 - Prob. 7RCh. 22 - Prob. 8RCh. 22 - Provide evidence that Creutzfeldt-Jakob disease is...Ch. 22 - NAME IT This organism causes meningitis and is...
Ch. 22 - Prob. 1MCQCh. 22 - Prob. 2MCQCh. 22 - Prob. 3MCQCh. 22 - Prob. 4MCQCh. 22 - Prob. 5MCQCh. 22 - Prob. 6MCQCh. 22 - Prob. 7MCQCh. 22 - Prob. 8MCQCh. 22 - Microscopic examination of cerebrospinal fluid...Ch. 22 - Prob. 10MCQCh. 22 - Prob. 1ACh. 22 - Prob. 2ACh. 22 - Prob. 1CAECh. 22 - Prob. 2CAECh. 22 - Prob. 3CAE
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